3993-79-1Relevant academic research and scientific papers
A concise Pd catalyzed cross coupling reaction along with deprotection for the synthesis of a new series of pyrimidine derivatives
Senthilkumar,Dominic Ravichandran,Rajesh
, p. 6868 - 6872 (2014)
A new series of 2-amino, 4-azepanone, 5-aryl substituted derivatives of pyrimidine compounds were synthesized for the first time from the commercially available 2-amino-4-hydroxypyrimidine. The key step in the reaction is a conceptually new single step palladium catalyzed cross coupling along with the deprotection of N,N-diisopropylformimidamide using bis(triphenylphosphine)palladium(II) dichloride (PdCl2(PPh3)2).
Synthesis and complementary self-association of novel lipophilic π-conjugated nucleoside oligomers
Camacho-García,Montoro-García,López-Pérez,Bilbao,Romero-Pérez,González-Rodríguez
supporting information, p. 4506 - 4513 (2015/04/14)
A series of lipophilic nucleosides comprising natural and non-natural bases that are π-conjugated to a short oligophenylene-ethynylene fragment has been synthesized. These bases comprise guanosine, isoguanosine, and 2-aminoadenosine as purine heterocycles, and cytidine, isocytosine and uridine as complementary pyrimidine bases. The hydrogen-bonding dimerization and association processes between complementary bases were also studied by 1H NMR and absorption spectroscopy in order to obtain the relevant association constants.
A convenient synthesis of N,N'-dibenzyl-2,4-diaminopyrimidine-2'- deoxyribonucleoside and 1-Methyl-2'-deoxypseudoisocytidine
Wellington, Kevin W.,Ooi, Hua Chee,Benner, Steven A.
experimental part, p. 275 - 291 (2009/12/26)
The syntheses of N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deoxyribonucleoside and 1-methyl-2'-deoxypseudoisocytidine via Heck coupling are described. A survey of the attempts to use the Heck coupling to synthesize N,N'-dibenzyl-2,4-diaminopyrimidine-2'-deox
