399558-95-3

Upstream product

• 111647-36-0 5'-O-(4,4'-dimethoxytrityl)-3'-mesyl-2',3'-dideoxythymidine 
• 50-89-5 thymidine 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 40615-39-2 1-((2R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)- dione 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 143527-01-9 1-(2'-deoxy-3'-O-mesyl-5'-O-4,4'-dimethoxytrityl-β-D-threo-pentofuranosyl)-thymine 
• 60-24-2 2-hydroxyethanethiol 

Downstream Products

• 399558-96-4 3'-deoxy-3'-S-(1-vinylsulfinyl)-5'-O-(4,4'-dimethoxytrityl)thymidine 

Relevant academic research and scientific papers

TT dinucleotides containing an isoxazoline moiety: Synthesis and binding affinity study

We have prepared four diastereomers of TT dinucleotides containing an isoxazoline moiety and four dodecanucleotides incorporating these TT dinucleotides in the middle of the DNA sequence. We also have determined the melting temperatures of these modified oligonucleotides (Tm values) by measuring change in UV absorbance.