399559-48-9

Upstream product

• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 261900-93-0 (S_S)-(+)-3-chloro-2-(p-tolylsulfinyl)prop-2-ene 

Downstream Products

• 505085-60-9 tert-butyl (1'S,2'R,R_S)-2-hydroxy-1-(hydroxymethyl)-4-[(4-methylphenyl)sulfinyl]pent-4-enylcarbamate 
• 505085-61-0 tert-butyl (4R,5S,R_S)-2,2-dimethyl-4-{2-[(4-methylphenyl)sulfinyl]-2-propenyl}-1,3-dioxan-5-ylcarbamate 

Relevant academic research and scientific papers

Barbier-type diastereoselective allylation of α-amino aldehydes with an enantiopure 2-sulfinylallyl building block

An optimized procedure for the diastereoselective allylation under aqueous Barbier conditions of a series of α-amino aldehydes with our new chiral building block (Ss)-3-chloro-2-(p-tolylsulfinyl)-1-propene [(Ss)-1a] to afford enantiomerically pure sulfinylamino alcohols in good yields and diastereoselectivites is reported. High levels of diastereoinduction can be achieved from α-amino aldehydes configurationally related to natural α-amino acids.