39996-87-7

Usage

Uses

Used in Pharmaceutical Industry:
Diethyl [(2-pyridinyl)methyl]phosphonate is used as a building block for the production of pharmaceutical drugs. Its unique structure and properties make it a valuable component in the synthesis of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical industry, Diethyl [(2-pyridinyl)methyl]phosphonate is used as a building block for the production of pesticides and herbicides. Its versatility allows for the creation of effective and targeted agricultural chemicals.
Used in Asymmetric Catalysis:
Diethyl [(2-pyridinyl)methyl]phosphonate is used in the development of chiral ligands for asymmetric catalysis. Its unique structure contributes to the advancement of catalytic processes, leading to more efficient and selective chemical reactions.
Used in Synthesis of Biologically Active Molecules:
Diethyl [(2-pyridinyl)methyl]phosphonate also serves as a precursor for the synthesis of biologically active molecules. Its role in creating such molecules highlights its importance in the development of new pharmaceuticals and other bioactive substances.

InChI:InChI=1/C10H16NO3P/c1-3-13-15(12,14-4-2)9-10-7-5-6-8-11-10/h5-8H,3-4,9H2,1-2H3

Upstream product

• 4377-33-7 2-chloromethylpyridine 
• 122-52-1 triethyl phosphite 
• 762-04-9 phosphonic acid diethyl ester 

Downstream Products

• 129078-90-6 <(1-benzylpyridino)-2-methyl>phosphonic acid 
• 21882-07-5 Cu(pyridine-2-carboxylate)2 C12H8CuN2O4, violet 
• 1416861-34-1 (E)-(4aR,7R,8aS)-7-methyl-1-[(4-methylbenzene)sulfonyl]-5-(pyridin-2-ylmethylidene)decahydroquinoline 
• 1416861-41-0 (Z)-(4aR,7R,8aS)-7-methyl-1-[(4-methylbenzene)sulfonyl]-5-(pyridin-2-ylmethylidene)decahydroquinoline 
• 1262049-27-3 (5R,8S,11R,13S,14S,17S)-5',5',13-trimethyl-17-(pentafluoroethyl)-11-{4-[2-(pyridin-2-yl)ethyl]phenyl}-1,2,3,4,6,7,8,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxane]-5,17-diol 
• 1262049-28-4 (5R,8S,11R,13S,14S,17S)-5',5',13-trimethyl-17-(pentafluoroethyl)-11-{4-[(E)-2-(pyridin-2-yl)ethenyl]phenyl}-1,2,3,4,6,7,8,11,12,13,14,15,16,17-tetradecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxane]-5,17-diol 

Relevant academic research and scientific papers

Utilities of olefin derivatives

Compounds having an activity to enhance the expression of apoAI are provided. Compounds of formula (I): in which Ar1 and Ar2 are independently a phenyl, naphthyl, or monocyclic or bicyclic aromatic heterocyclic group, which may be optionally substituted; —X— is —N═CZ2-, —CY2═CZ2-, —CY2Y3—CHZ2-, —S—, —O—, or the like; Y1, Y2, Y3, Z1 and Z2 are independently a hydrogen, a halogen, a lower alkyl, a phenyl, or the like; Z1 and Z2 may be independently a linker group that may combine with Ar2 and Ar1 to form a condensed ring; m is 0 or 1, and n is 0 to 2; a prodrug thereof, a pharmaceutically acceptable salt or solvate of them; are disclosed.

SYNTHESIS AND CHARACTERIZATION OF OXIMINO PYRIDOYL PHOSPHONATES

Oximino pyridoyl phosphonates were synthesised as well as the methiodide of oximino-2-pyridoyl phosphonate.All these compounds along with their intermediates have been characterized by spectroscopic methods and by elemental analysis.Key words: Phosphite, Michaelis-Becker reaction, Oximino pyridoyl phosphonates.

A SIMPLE AND CONVENIENT SYNTHESIS OF 2-PHOSPHONOMETHYL PYRIDINES

The Michaelis-Becker-Nylen reaction is well suited for the synthesis of 2-phosphonomethyl pyridines.We have improved this four steps method in a one pot reaction using commercial reagents.By this general procedure we have prepared seven new 2-phosphonomethyl pyridines (Ia-g) under mild conditions with higher yields.Key words: 2-phosphono pyridines; 2-phosphonomethyl pyridines; Michaelis-Becker-Nylen reaction; new phosphonates; potential ligands.

Photolysis of Pyridylmethyl- and Pyridiniomethylphosphonic Acids

Upon UV-irradiation, the C-P bond of (4-pyridylmethyl)phosphonic acid cleaved only near the isoelectronic point to give 4-methylpyridinium phophate, while (1-benzyl-4-pyridiniomethyl)phosphonic acid underwent C-P bond cleavage above pH 4 to give 1-benzyl-4-methylpyridinium phosphate.On the other hand, the C-P bond of (2-pyridylmethyl)phosphonic acid cleaved under pH region of about 1 to 2, while (1-benzyl-2-pyridiniomethyl)phosphonic acid underwent C-P bond cleavage above pH4.

PHOTODEPHOSPHORYLATION OF PHOSPHONIC ACIDS

Photolysis of phosphonic acids in an alkaline aqeous solution gave 1-benzyl-methylpyridinium phosphates by the photocleavage of the C-P bond.