40000-60-0Relevant academic research and scientific papers
Synthesis of novel 3-alkyl-3′,4′,5,7-tetrahydroxyflavones
Seixas, Raquel S. G. R.,Pinto, Diana C. G. A.,Silva, Artur M. S.,Cavaleiro, Jos A. S.
, p. 718 - 724 (2008/12/22)
Novel 3-alkyl-3′,4′,5,7-tetrahydroxyflavones have been prepared. The synthetic strategy involves the preparation of 1-(2-hydroxy-4,6-dimethoxyphenyl)alkan-1-ones from the FriedelCrafts acylation of phloroglucinol followed by methylation. These key compounds were submitted to the three-step BakerVenkataraman method, giving the 3-alkyl-3′,4′, 5,7-tetramethoxyflavones, which were demethylated with boron tribromide. CSIRO 2008.
