400010-25-5Relevant academic research and scientific papers
Heterogeneous catalysis: Ni/C-catalyzed cross-couplings en route to allylated aromatics: Application to a precursor to coenzyme Q10
Lipshutz, Bruce H.,Frieman, Bryan,Pfeiffer, Steven S.
, p. 2110 - 2116 (2002)
The readily available, heterogeneous, and inexpensive catalyst nickel-on-charcoal (Ni/C) can be used to mediate couplings between vinyl alanes and benzylic chlorides under very mild conditions and in good yields. Although such allylated aromatics are them
Controlling regiochemistry in negishi carboaluminations. Fine tuning the ligand on zirconium
Lipshutz, Bruce H.,Butler, Tom,Lower, Asher
, p. 15396 - 15398 (2007/10/03)
The species on the zirconocene catalyst is changed from two Cp's to the Brintzinger ligand and catalytic amounts of MAO are used to usually effect a >99% regiocontrol of Negishi carboaluminations of 1-alkynes in toluene. Copyright
A short, highly efficient synthesis of coenzyme Q10
Lipshutz, Bruce H.,Mollard, Paul,Pfeiffer, Steven S.,Chrisman, Will
, p. 14282 - 14283 (2007/10/03)
The most efficient synthesis reported to date of ubiquinone (CoQ10) is described. A sequence consisting of six operations is involved which leads to crystalline material in an overall yield of >64%. Copyright
