400051-58-3Relevant articles and documents
Synthesis of a prenylated and immunosuppressive marine galactosphingolipid with cyclopropane-containing alkyl chains: (2S,3R,11S,12R,2?R,5?Z,11?S,12?R)-Plakoside A and its (2S,3R,11R,12S,2?R,5?Z,11?R,12?)Isomer
Seki, Masanori,Mori, Kenji
, p. 3797 - 3809 (2001)
Plakoside A (1) {(2S,3R,11R*,12S*)-2-[(2? R,5? Z,11? R*, 12? S*)-2?-hydroxy-11?, 12?-methylene-5?-docosen-amido]-1-O-[2′-O- (3″-methyl-2″-butenyl)-β-D-galactopyranosyl]-11,12- methylene-1,3-docosanediol} is a prenylated galactosphingolipid isolated as an immunosuppressant from the marine sponge Plakortis simplex. (2S,3R,11S,12R,2? R,5? Z,11? S,12? R)-Plakoside A (1) has been synthesized by combining the sphingosine part 16, the α-hydroxy acid part 28, and the prenylated sugar part 33. (2S,3R,11R,12S,2? R,5? Z,11? R,12? S)-Plakoside A (1′) has also been synthesized.