40013-87-4 Usage
Uses
Used in Pharmaceutical Industry:
24(R), 25-DIHYDROXYVITAMIN D3 is used as a therapeutic agent for bone health due to its role in regulating bone metabolism, calcium and phosphate balance, and its influence on bone mineralization and resorption.
Used in Autoimmune and Inflammatory Conditions:
24(R), 25-DIHYDROXYVITAMIN D3 is used as an immunomodulatory agent for its anti-inflammatory properties, making it a potential treatment for autoimmune and inflammatory conditions.
Used in Cancer Prevention and Treatment:
24(R), 25-DIHYDROXYVITAMIN D3 is used as a preventative and therapeutic agent in oncology due to its involvement in the regulation of cell proliferation and differentiation, indicating its potential role in cancer prevention and treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 40013-87-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,1 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 40013-87:
(7*4)+(6*0)+(5*0)+(4*1)+(3*3)+(2*8)+(1*7)=64
64 % 10 = 4
So 40013-87-4 is a valid CAS Registry Number.
40013-87-4Relevant academic research and scientific papers
Stereoselective Introduction of Hydroxy Groups into the Cholesterol Side Chain. Preparation of (24R)- and (24S)-24,25-Dihydroxy- and (25R)- and (25S)-25,26-Dihydroxyvitamin D3 by Asymmetric Synthesis
Koizumi, Naoyuki,Ishiguro, Masaji,Yasuda, Mitsuhiro,Ikekawa, Nobuo
, p. 1401 - 1410 (2007/10/02)
24,25-Epoxy-26-hydroxy-3β-tetrahydropyranyloxycholest-5-enes (7a) and (8a), prepared by asymmetric epoxidation of the allylic alcohol (4), and 24-hydroxy-3β-tetrahydropyranyloxycholesta-5,25-dienes (11) and (12), synthesized by asymmetric reduction of the enone (6), were stereoselectively converted into 25,26-and 24,25-dihydroxycholesterol derivatives, which could be transformed into 25,26- and 24,25-dihydroxyvitamin D3.The highly stereoselective epoxide cleavage of 26-benzoyloxy-24,25-epoxides (7b), (8b), (25), and (26) was found to proceed with retention at C-24.
Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol
-
, (2008/06/13)
Syntheses of 24R,25- and 24S,25-dihydroxycholecalciferol, the biologically important metabolite and derivative, respectively, of vitamin D3, are described.
