40016-70-4

Basic information

• Product Name: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE
• Synonyms: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE;METHYL 3-METHYLQUINOXALINE-2-CARBOXYLATE-1,4-DIOXIDE;2-(methoxycarbonyl)-3-methyl-1-oxoquinoxalin-1-ium-4(1H)-olate
• CAS NO: 40016-70-4
• Molecular Formula: C11H10N2O4
• Molecular Weight: 234.21
• Mol File: 40016-70-4.mol
• Article Data: 9

Chemical Properties

• Melting Point: 171 °C
• Appearance: /
• CAS DataBase Reference: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE(40016-70-4)
• EPA Substance Registry System: 2-(METHOXYCARBONYL)-3-METHYLQUINOXALINEDIIUM-1,4-DIOLATE(40016-70-4)

Safety Data

• Hazardous Substances Data: 40016-70-4(Hazardous Substances Data)

Usage

General Description

2-(Methoxycarbonyl)-3-methylquinoxalinediium-1,4-diolate is a chemical compound that is a diquaternary ammonium salt. It is primarily used as a vasodilator and antiplatelet agent, and has shown potential in the treatment of cardiovascular diseases such as angina and peripheral vascular disease. The compound has been studied for its ability to relax smooth muscle and improve blood flow, and has been used experimentally for the treatment of erectile dysfunction. Additionally, it has been investigated for its potential role in the prevention of ischemia-reperfusion injury and as a potential therapeutic agent for neurological disorders. Overall, 2-(Methoxycarbonyl)-3-methylquinoxalinediium-1,4-diolate shows promise as a multifunctional compound with potential therapeutic applications in various medical conditions.

InChI:InChI=1/C11H10N2O4/c1-7-10(11(14)17-2)13(16)9-6-4-3-5-8(9)12(7)15/h3-6H,1-2H3

Upstream product

• 13297-18-2 2-ethoxycarbonyl-3-methylquinoxaline 1,4-dioxide 
• 480-96-6 benzofurazan oxide 
• 14205-39-1 methyl 3-aminocrotonate 
• 105-45-3 acetoacetic acid methyl ester 

Downstream Products

• 61522-54-1 methyl 3-methylquinoxaline-2-carboxylate 
• 61522-53-0 2-Methylchinoxalin-3-carbonsaeuremethylester-1-oxid 
• 61528-76-5 3-Methylchinoxalin-2-carbonsaeuremethylester-1-oxid 

Relevant articles and documents

Silica gel catalyzed synthesis of quinoxialine 1,4-dioxides under solvent-free conditions using microwave irradiation

We report on the simple and quick synthesis of quinoxaline 1,4-dioxides in solvent-free conditions under microwave irradiation. Heating of various benzofuroxans and β-ketoesters or 1,3-diketones adsorbed on silica gel in a microwave oven for two minutes affords diverse biologically attractive quinoxaline 1,4-dioxides in high to excellent yields. Silica gel functions not only as support using microwave but also as catalyst and dehydration reagent.

Synthesis of new quinoxaline-2-carboxylate 1,4-dioxide derivatives as anti-Mycobacterium tuberculosis agents

Twenty-nine new 6(7)-substituted quinoxaline-2-carboxylate 1,4-dioxide derivatives were synthesized and evaluated for in vitro antituberculosis activity. In general, the in vitro activity is significantly affected by substituents on the quinoxaline nucleu

The reactions of benzofuroxan with carbonyl compounds on the surface of solid catalysts

The cyclocondensations of benzofuroxan 1a with carbonyl compounds were smoothly and efficiently carried out by the adsorption of the components on the surface of silica gel or a molecular sieve to form a 2,3-disubstituted quinoxaline 1,4-dioxide. When the