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1-(2-CHLOROPHENYL)PROPYLAMINE-HCl, also known as 2-Chloroamphetamine hydrochloride, is a phenethylamine derivative with psychoactive and stimulant properties. It is a potent serotonergic neurotoxin that structurally resembles amphetamines and functions as a releasing agent for serotonin, dopamine, and norepinephrine. 1-(2-CHLOROPHENYL)PROPYLAMINE-HCl is primarily utilized in laboratory research to investigate the impacts of serotonergic neurotoxins on the central nervous system and has been explored for its potential therapeutic uses in conditions such as depression and obesity.

40023-85-6

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40023-85-6 Usage

Uses

Used in Pharmaceutical Research:
1-(2-CHLOROPHENYL)PROPYLAMINE-HCl is used as a research chemical for studying the effects of serotonergic neurotoxins on the central nervous system. It aids in understanding the mechanisms of action and potential therapeutic applications in various neurological and psychiatric conditions.
Used in Therapeutic Applications:
In the field of medicine, 1-(2-CHLOROPHENYL)PROPYLAMINE-HCl is used as a potential treatment for conditions such as depression and obesity. Its serotonergic and stimulant properties are being investigated for their potential to modulate mood and appetite, offering new avenues for treatment.
Used in Toxicological Studies:
1-(2-CHLOROPHENYL)PROPYLAMINE-HCl is also used in toxicological research to explore the effects of neurotoxins on the brain and develop strategies for mitigating their harmful impacts.

Check Digit Verification of cas no

The CAS Registry Mumber 40023-85-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,2 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40023-85:
(7*4)+(6*0)+(5*0)+(4*2)+(3*3)+(2*8)+(1*5)=66
66 % 10 = 6
So 40023-85-6 is a valid CAS Registry Number.

40023-85-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-Chlorophenyl)propan-1-amine hydrochloride

1.2 Other means of identification

Product number -
Other names 1-(2-chlorophenyl)propan-1-amine,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40023-85-6 SDS

40023-85-6Upstream product

40023-85-6Downstream Products

40023-85-6Relevant academic research and scientific papers

2-Mercaptoimidazoles, a new class of potent CCR2 antagonists

Van Lommen, Guy,Doyon, Julien,Coesemans, Erwin,Boeckx, Staf,Cools, Marina,Buntinx, Mieke,Hermans, Bart,VanWauwe, Jean

, p. 497 - 500 (2007/10/03)

We describe the synthesis and SAR of a new class of CCR2 antagonists based on a 2-mercaptoimidazole scaffold. The initial lead 1a was optimized to the 3,4-disubstituted analogues 1p-(S) and 1q-(S), which have IC50 values in the MCP-1 induced Ca

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

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Page 251, (2008/06/13)

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

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Page 127; 128, (2008/06/13)

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

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Page 129, (2008/06/13)

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

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