40027-64-3 Usage
Uses
Used in Pharmaceutical Research:
3,5-DIMETHYL-1H-PYRAZOLE-1-CARBOXAMIDIN& is used as a building block in pharmaceutical research for the synthesis of various biologically active compounds. Its unique structure and chemical properties make it a promising candidate for the development of new drugs with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, 3,5-DIMETHYL-1H-PYRAZOLE-1-CARBOXAMIDIN& is utilized as a key intermediate for the preparation of complex organic molecules. Its reactivity and functional groups allow for a wide range of chemical transformations, facilitating the synthesis of diverse chemical entities.
Used in Medicinal Chemistry:
3,5-DIMETHYL-1H-PYRAZOLE-1-CARBOXAMIDIN& is employed in medicinal chemistry as a structural component of potential drug candidates. Its incorporation into molecular frameworks can enhance the pharmacological properties of compounds, such as potency, selectivity, and bioavailability, contributing to the advancement of novel therapeutic agents.
Used in Drug Discovery:
In drug discovery processes, 3,5-DIMETHYL-1H-PYRAZOLE-1-CARBOXAMIDIN& serves as a versatile starting material for the design and optimization of new chemical entities. Its unique chemical features and compatibility with various synthetic strategies make it an attractive option for exploring new therapeutic opportunities and addressing unmet medical needs.
Check Digit Verification of cas no
The CAS Registry Mumber 40027-64-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,2 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 40027-64:
(7*4)+(6*0)+(5*0)+(4*2)+(3*7)+(2*6)+(1*4)=73
73 % 10 = 3
So 40027-64-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H12N4.ClH/c1-4-5(2)10-11(6(4)3)7(8)9;/h1-3H3,(H3,8,9);1H
40027-64-3Relevant academic research and scientific papers
3,5-dimethyl-1H-pyrazole-1-carboxamidine hydrochloride preparation method
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Paragraph 0013; 0014; 0015, (2016/11/24)
The invention discloses a 3,5-dimethyl-1H-pyrazole-1-carboxamidine hydrochloride preparation method. According to the invention, the compound 3,5-dimethyl-1H-pyrazole-1-carboxamidine hydrochloride with a complex structure is synthesized with the raw materials of aminoguanidine carbonate, acetylacetone and the like. The product yield is high, and the product has good crystallization effect and high purity, such that high-purity standard sample or sample can be provided for subsequent chemical and biological experiments.
1H-Pyrazole-1-carboxamidines: New inhibitors of nitric oxide synthase
Lee, Younghee,Martasek, Pavel,Roman, Linda J,Silverman, Richard B
, p. 2771 - 2774 (2007/10/03)
1H-Pyrazole-1-carboxamidines were prepared as potential inhibitors of the three isozymes of nitric oxide synthase. All of the compounds were found to be competitive inhibitors of all three isoforms. The most selective compound prepared was 1H-pyrazole-N-(3-aminomethylanilino)-1-carboxamidine (14), which is 100-fold selective for nNOS over eNOS with a K(i) value of 2μM. (C) 2000 Elsevier Science Ltd.
