400643-63-2

Upstream product

• 67304-08-9 (R)-3-isopropyl-6-oxoheptanal 
• 400643-66-5 Acetic acid (S)-3-(2-benzyloxy-ethyl)-4-methyl-pentyl ester 
• 400643-65-4 Acetic acid (S)-3-(2-hydroxy-ethyl)-4-methyl-pentyl ester 
• 82425-87-4 (R)-5-(1-methylethyl)-7-hydroxyheptan-2-one 
• 124484-44-2 Acetic acid (R)-3-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-methyl-pentyl ester 
• 124469-35-8 (R)-5-[2-(tert-Butyl-diphenyl-silanyloxy)-ethyl]-6-methyl-heptan-2-one 
• 105897-85-6 (R)-3-(1-methylethyl)-6-oxoheptanal dimethylacetal 
• 1195-31-9 (+)-p-menth-1-ene 
• 5989-27-5 D-limonene 
• 400643-67-6 (R)-3-(2-Benzyloxy-ethyl)-4-methyl-pentan-1-ol 

Downstream Products

• 400643-70-1 (2S,3S,5S)-5-(2-Benzyloxy-ethyl)-2-[(3S,5S,8R,9S,10S,13S,14S)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-heptan-3-ol 
• 400643-71-2 (2S,3R,5S)-5-(2-Benzyloxy-ethyl)-2-[(3S,5S,8R,9S,10S,13S,14S)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-heptan-3-ol 
• 400643-80-3 (3S,5S,6S)-6-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-3-isopropyl-heptane-1,5-diol 
• 400643-81-4 (3S,5R,6S)-6-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-3-isopropyl-heptane-1,5-diol 
• 400643-84-7 (4R,6S)-6-{(S)-1-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethyl}-4-isopropyl-tetrahydro-pyran-2-one 
• 400643-85-8 (4R,6R)-6-{(S)-1-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethyl}-4-isopropyl-tetrahydro-pyran-2-one 
• 400643-59-6 (4R,6S)-6-{(S)-1-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethyl}-4-isopropyl-tetrahydro-pyran-2-ol 
• 400643-60-9 (4R,6R)-6-{(S)-1-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-(tert-Butyl-diphenyl-silanyloxy)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl]-ethyl}-4-isopropyl-tetrahydro-pyran-2-ol 
• 400643-73-4 (2S,5S)-5-(2-Benzyloxy-ethyl)-2-[(3S,5S,8R,9S,10S,13S,14S)-3-(tert-butyl-diphenyl-silanyloxy)-10,13-dimethyl-2,3,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-6-methyl-heptan-3-one 

Relevant academic research and scientific papers

Stereocontrolled synthesis of contignasterol's side chain

The four models of the contignasterol's side chains (2-5) have been stereospecifically prepared. The key reaction in the synthesis is a dimethylaluminum chloride-mediated 'ene' reaction between the steroid derivative 6 and the pseudo-enantiomeric aldehydes 7 and 8.