400648-65-9

Upstream product

• 400648-63-7 3-(4-aminophenyl)-2-{3-[(2,2-dimethylpropionyl)isobutylamino]-4-methoxyphenyl} propionic acid ethyl ester 
• 400648-62-6 2-{3-[(2,2-dimethyl-propionyl)-isobutyl-amino]-4-methoxy-phenyl}-3-(4-nitro-phenyl)-propionic acid ethyl ester 
• 400648-60-4 ethyl 2-(3-amino-4-methoxyphenyl)-3-(4-nitrophenyl)propanoate 
• 824402-51-9 (4-Methoxy-3-{[1-phenyl-meth-(E)-ylidene]-amino}-phenyl)-acetic acid ethyl ester 
• 400648-57-9 4-methoxy-3-nitrophenylacetic acid ethyl ester 
• 229328-97-6 3,5-dichloroisonicotinoyl chloride 
• 400648-61-5 2-[(3-isobutylamino)-4-methoxy phenyl]-3-(4-nitrophenyl)propionic acid ethyl ester 

Relevant academic research and scientific papers

2,3-Diphenylpropionic acids as potent VLA-4 antagonists

2,3-Diphenylpropionic acid derivatives as highly potent VLA-4 antagonists are described. One representative compound, 9cc has inhibited intercellular adhesion by a VCAM-1/VLA-4 interaction with an IC50 of 1.7 nM, and has good pharmacokinetics a

2,3-DIPHENYLPROPIONIC ACID DERIVATIVES OR THEIR SALTS, MEDICINES OR CELL ADHESION INHIBITORS CONTAINING THE SAME, AND THEIR USAGE

A 2,3-diphenylpropionic acid derivatives or the salts represented by general formula (1) below; and pharmaceutical compositions and cell adhesion inhibitors comprising the derivatives or the salts as the active ingredient. In the formula, A, B and C indep