40073-37-8 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
4-Isoquinolinamine,3-bromo-(9CI) is utilized as a chemical intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and potential medicinal properties make it a valuable candidate for the development of new drugs targeting a range of diseases and conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-Isoquinolinamine,3-bromo-(9CI) serves as a key building block for the design and synthesis of novel bioactive molecules. Its presence in the quinoline alkaloids family, known for their diverse biological activities, positions it as a promising scaffold for the creation of new therapeutic agents.
Used in Chemical Synthesis:
4-Isoquinolinamine,3-bromo-(9CI) is employed as a reagent in various chemical synthesis processes. Its unique functional groups and chemical properties allow for the formation of new compounds with potential applications in different industries, including pharmaceuticals, agrochemicals, and materials science.
Used in Analytical Chemistry:
As a chemical compound with distinct properties, 4-Isoquinolinamine,3-bromo-(9CI) can be used in analytical chemistry for the development of new methods and techniques for the detection, quantification, and analysis of various substances. Its unique characteristics may contribute to the advancement of analytical methodologies and the improvement of existing ones.
Check Digit Verification of cas no
The CAS Registry Mumber 40073-37-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,0,7 and 3 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 40073-37:
(7*4)+(6*0)+(5*0)+(4*7)+(3*3)+(2*3)+(1*7)=78
78 % 10 = 8
So 40073-37-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H7BrN2/c10-9-8(11)7-4-2-1-3-6(7)5-12-9/h1-5H,11H2
40073-37-8Relevant academic research and scientific papers
Synthesis of fused systems in the isoquinoline series: Oxazolo- and pyrrolo[3,2-c]isoquinolines
Briere, Jean-Francois,Dupas, Georges,Queguiner, Guy,Bourguignon, Jean
, p. 1371 - 1383 (2007/10/03)
In order to synthesize the pyrrolo[3,2-c]isoquinoline structure, three different routes starting from readily available isoquinolines were tried. The ring closure reaction of a malonic derivative of 4-amino-3- bromoisoquinoline led to an oxazolo[3,2-c]isoquinoline instead of the target molecule. This latter was obtained via Sonagashira coupling reaction followed by ring closure under basic conditions. A study of the lithiation of the N- sulfonated pyrrolo[3,2-c]isoquinoline was undertaken. After optimization of the lithiation conditions, various 2-substituted pyrrolo[3,2-c]isoquinolines were obtained and their oxidation reactions studied.
PHOTOLYSIS OF PYRIDYL, QUINOLYL, AND ISOQUINOLYL AZIDES IN HYDROHALOGENOIC ACIDS
Sawanishi, Hiroyuki,Hirai, Toyoko,Tsuchiya, Takashi
, p. 1043 - 1046 (2007/10/02)
Photolysis of 4-azido-pyridine and -quinoline in hydrohalogenoic acids gave the 3-amino-4-halogeno compounds (2) via azirine or azacycloheptatetraene intermediates, whereas their N-oxides (4), under similar conditions, gave the 4-amino-3-halogeno compounds (5) presumably via nitrenium ion intermediates.In the 3-azidoquinoline and 4-azidoisoquinoline series, both free bases (6a, 8a) and N-oxides (6b, 8b) gave similar results to 4-azidopyridine and -quinoline N-oxides (4).
