40073-45-8Relevant academic research and scientific papers
1-Amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid as a Tic mimetic: Application in the synthesis of potent human melanocortin-4 receptor selective agonists
Bakshi, Raman K.,Hong, Qingmei,Olson,Ye, Zhixiong,Sebhat, Iyassue K.,Weinberg, David H.,MacNeil, Tanya,Kalyani, Rubana N.,Tang, Rui,Martin, William J.,Strack, Alison,McGowan, Erin,Tamvakopoulos, Constantin,Miller, Randy R.,Stearns, Ralph A.,Tang, Wei,Maclntyre, D. Euan,Van Der Ploeg, Lex H. T.,Patchett, Arthur A.,Nargund, Ravi P.
, p. 3430 - 3433 (2007/10/03)
The discovery of 1-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid analogs as potent human melanocortin-4 selective agonists is described.
SUBSTITUTED PIPERIDINES AS MELANOCORTIN RECEPTOR AGONISTS
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Page 22, (2008/06/13)
Certain novel 4-substituted piperidine compounds are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction.
