400771-44-0 Usage
Description
1-(3-ISOPROPOXYPHENYL)METHANAMINE, with the molecular formula C11H17NO, is an amine derivative characterized by the presence of a phenyl group and an isopropoxy group attached to the amino group. This chemical compound is primarily utilized in the synthesis of pharmaceuticals and agrochemicals, and it may also find applications in materials science and organic chemistry. Due to its potentially hazardous nature, it is crucial to handle 1-(3-ISOPROPOXYPHENYL)METHANAMINE with care to avoid skin, eye, and respiratory irritation.
Uses
Used in Pharmaceutical Industry:
1-(3-ISOPROPOXYPHENYL)METHANAMINE is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(3-ISOPROPOXYPHENYL)METHANAMINE is used as a building block in the creation of agrochemicals, potentially enhancing crop protection and yield through the development of novel pesticides and other related products.
Used in Materials Science:
1-(3-ISOPROPOXYPHENYL)METHANAMINE is utilized in materials science for its potential to contribute to the development of new materials with unique properties, such as improved strength, flexibility, or chemical resistance.
Used in Organic Chemistry:
As an amine derivative, 1-(3-ISOPROPOXYPHENYL)METHANAMINE is employed in organic chemistry for its reactivity in various chemical reactions, facilitating the synthesis of complex organic molecules for research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 400771-44-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,7,7 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 400771-44:
(8*4)+(7*0)+(6*0)+(5*7)+(4*7)+(3*1)+(2*4)+(1*4)=110
110 % 10 = 0
So 400771-44-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H15NO/c1-8(2)12-10-5-3-4-9(6-10)7-11/h3-6,8H,7,11H2,1-2H3
400771-44-0Relevant articles and documents
Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency
Egbertson, Melissa,McGaughey, Georgia B.,Pitzenberger, Steven M.,Stauffer, Shaun R.,Coburn, Craig A.,Stachel, Shawn J.,Yang, Wenjin,Barrow, James C.,Neilson, Lou Anne,McWherter, Melody,Perlow, Debra,Fahr, Bruce,Munshi, Sanjeev,Allison, Timothy J.,Holloway, Katharine,Selnick, Harold G.,Yang, Zhiqiang,Swestock, John,Simon, Adam J.,Sankaranarayanan, Sethu,Colussi, Dennis,Tugusheva, Katherine,Lai, Ming-Tain,Pietrak, Beth,Haugabook, Shari,Jin, Lixia,Chen,Holahan, Marie,Stranieri-Michener, Maria,Cook, Jacquelynn J.,Vacca, Joseph,Graham, Samuel L.
supporting information, p. 4812 - 4819 (2015/10/28)
The IC50 of a beta-secretase (BACE-1) lead compound was improved ～200-fold from 11 μM to 55 nM through the addition of a single methyl group. Computational chemistry, small molecule NMR, and protein crystallography capabilities were used to com
SPIROPIPERIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE
-
Page/Page column 27, (2010/11/25)
The present invention is directed to spiropiperidine compounds of formula (I) and tautomers thereof, which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as
