40080-28-2Relevant academic research and scientific papers
Some synthetic applications of 2,3-dichloro-N-phenylmaleimide: A novel synthesis of 2-phenylpyrrolo[3,4-b]quinoxaline-1,3-diones. I
Hanaineh-Abdelnour, Leila,Bayyuk, Shibly,Theodorie, Rima
, p. 11859 - 11870 (2007/10/03)
2,3-Dichloro-N-phenylmaleimide 2 undergoes nucleophilic substitution reactions by a variety of nucleophiles giving either monosubstituted 5 or disubstituted 3 products. Treatment of 5 with sodium azide at room temperature results in cyclization to the corresponding 2-phenylpyrrolo[3,4- b]quinoxaline-1,3-diones 6, while at higher temperatures 5 is reduced to the 2-amino-amino-N-phenylmaleimides 7.
