400845-02-5Relevant articles and documents
Design, synthesis and in vitro evaluation on HRPE cells of ascorbic and 6-bromoascorbic acid conjugates with neuroactive molecules
Manfredini, Stefano,Vertuani, Silvia,Pavan, Barbara,Vitali, Federica,Scaglianti, Martina,Bortolotti, Fabrizio,Biondi, Carla,Scatturin, Angelo,Prasad, Puttur,Dalpiaz, Alessandro
, p. 5453 - 5463 (2007/10/03)
Preliminary investigations allowed us to anticipate that conjugation of nipecotic acid with l-ascorbate (AA) gave a prodrug endowed with anticonvulsant activity in mice. In view of these results, and in order to get deepen insight into the molecular aspec