40098-44-0Relevant academic research and scientific papers
TOTAL SYNTHESIS OF PROSTAGLANDINS. IV*. SYNTHESIS OF 2-(6-ALKOXYCARBONYLHEXYL)CYCLOPENT-2-EN-1-ONES
Bokaldere, R. P.,Liepinya, A. Ya.,Lozha, E. V.,Lolya, D. O.,Freimanis, Ya. F.
, p. 2119 - 2123 (2007/10/02)
A preparative method was developed for the synthesis of 2-(6-alkoxycarbonylhexyl)cyclopent-2-en-1-ones by the bromination of the respective 2-(6-alkoxycarbonylhexyl)cyclopentan-1-ones with N-bromosuccinimide, followed by dehydrobromination of the bromine-substituted compounds and isomerization of the 2-(6-alkoxycarbonylhexylidene)cyclopentan-1-ones formed as side products.
Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones
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, (2008/06/13)
This disclosure describes novel 4-oxy-2-substituted-cyclopent-2-en-1-ones useful as intermediates for the preparation of homo and nor prostaglandins of the E2, E3 and F series.
Novel 11-hydroxy-9-keto-5,6-cis-13,14-cis-prostadienoic acid derivatives
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, (2008/06/13)
This disclosure describes certain 11-hydroxy and 11-deoxy-9-keto(or hydroxy)-prostanoic acid derivatives useful as bronchodilators, hypotensive agents, anti-ulcer agents, or as intermediates.
Hydro substituted prostanoic acids and esters
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, (2008/06/13)
This disclosure describes certain 11-hydroxy and 11-deoxy-9-keto (or hydroxy)prostanoic acid derivatives useful as bronchodilators, anti-ulcer agents, or as intermediates.
1-Alkoximino-2-(ω-substituted alkyl)-2-cyclopentenes
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, (2008/06/13)
This disclosure describes certain 1-alkoximino-2-(ω-substituted-alkyl)-2-cyclopentenes useful as intermediates for the preparation of homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid which have antimicrobial activity and prostaglandin-like hypotensive activity.
Derivatives of 9-hydroxy-13-trans-prostenoic acid
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, (2008/06/13)
This disclosure describes certain 15-deoxy prostanoic acid derivatives having a hydroxy group further along in the beta-chain, useful as bronchodilators, hypotensive agents, anti-ulcer agents, or as intermediates.
3-Alkyl-2-(6-carboxyhexyl)cyclopentanones and esters and salts thereof
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, (2008/06/13)
This disclosure describes compounds of the class of substituted 9-oxoprostanoic acids and the esters and cationic salts thereof, useful as antimicrobial agents, hypotensive agents, anti-ulcer agents, or as intermediates, and novel processes for preparing the same.
Derivatives of 9-oxo-13-trans-prostenoic acid esters
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, (2008/06/13)
This disclosure describes homologues, analogues, congeners, and derivatives of 9-oxo-13-trans-prostenoic acid and of 9-hydroxy-13-trans-prostenoic acid, having antimicrobial activity and prostaglandin-like hypotensive activity.
13-Sulfa-prostaglandins
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, (2008/06/13)
Sulfides of the general formula SPC1 Wherein R1 is H or alkyl, R2 is =O, (H,OH), or (H,lower-acyloxy), R3 is H, OH or lower-acyloxy, R4 is alkyl or alkyl substituted by F, OH, lower-acyloxy, phenyl or p-tolyl, and A is alkylene which can be mono- or polysubstituted by F, and the physiologically acceptable salts thereof, possess, in addition to a blood-pressure-lowering activity, prostaglandin-type and antiprostaglandin-type effects.
