401-94-5

Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-5-Nitrobenzotrifluoride is used as a key intermediate in the synthesis of various pharmaceutical compounds for [application reason]. Its unique properties and reactivity make it an essential component in the development of new drugs and organic chemicals.
Used in Drug Manufacturing:
3-Amino-5-Nitrobenzotrifluoride is used as a building block in the production of various drugs, contributing to their therapeutic effects and improving patient outcomes.
Used in Organic Chemistry Research:
3-AMINO-5-NITROBENZOTRIFLUORIDE is utilized as a reagent or catalyst in various organic chemical reactions, enabling the synthesis of complex organic molecules and advancing scientific research in the field.

Upstream product

• 401-99-0 3,5-dinitrobenzotrifluoride 
• 64-17-5 ethanol 
• 98-46-4 3-trifluoromethylnitrobenzene 

Downstream Products

• 349-57-5 3-nitro-5-(trifluoromethyl)phenol 
• 401-93-4 5-chloro-3-trifluoromethyl-nitrobenzene 
• 402-00-6 acetic acid-(3-nitro-5-trifluoromethyl-anilide) 
• 2559-68-4 (3-nitro-5-trifluoromethyl-phenyl)-phenyl sulfone 
• 55225-74-6 4-(fluorosulfonyl)-3'-(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-63-3 4-(4-chlorophenoxy)-3'-(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-18-8 4-(trifluoromethylthio)-3'-(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-76-8 2-(ethylsulfonyl)-3',5-bis(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-47-3 4-(2-chloro-1,1,2-trifluoroethoxy)-3,3'-bis(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-59-7 4-(1,1,2,3,3,3-hexafluoro-n-propoxy)-3,3'-bis(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-43-9 4-(2-chloro-1,1,2-trifluoroethoxy)-3'-(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-68-8 3,3',5-tris(trifluoromethyl)-5'-nitrocarbanilide 
• 55225-67-7 3,3'-bis(trifluoromethyl)-5'-nitrocarbanilide 
• 62606-03-5 (3-Nitro-5-trifluoromethyl-phenyl)-(2,4,6-trinitro-phenyl)-amine 

Relevant academic research and scientific papers

A Convenient, Efficient, and Environmentally Benign Method for Preparing Nitroanilines

An efficient method for the catalytic monoreduction of aromatic dinitro compounds to nitroanilines is reported. In the presence of selenium catalyst, the dinitroaromatic compounds are selectively reduced by CO/H2O to the corresponding nitroanilines under atmospheric pressure. The mono-reduction occurs in high selectivity regardless of the substitution groups on the aromatic ring without affecting other reducible functional groups.

Substituted alkylamine derivatives and methods of use

Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Herbicidally active phenylsubstituted 5-and 6-membered heterocyclic compounds

A compound of formula (I): STR1 where E is oxygen or sulphur; A is CR3 or N where R3 is hydrogen or hydrocarbyl; D completes a 5 or 6-membered non-aromatic heterocyclic ring which optionally contains additional heteroatoms selected from oxygen, nitrogen or sulphur and which is optionally substituted by an optionally substituted lower hydrocarbyl group, or an optionally substituted heteroaryl group; R1 and R2 are each independently hydrogen; optionally substituted lower hydrocarbyl, or optionally substituted heteroaryl, or R1 and R2 together with the nitrogen atom to which they are attached, form a heterocyclic ring; Z represents halogen optionally substituted lower hydrocarbyl, optionally substituted lower hydocarbyloxy, optionally substituted lower hydrocarbylthio, hydrocarbylsulphinyl or hydrocarbylsulphonyl, cyano, nitro, CHO, NHOH, ONR7' R7", SF5 ; CO (optionally substituted lower hydrocarbyl), acylamino, COOR7, SO2 NR8 R9, CONR10 R11, OR12 or NR13 R14 where R7, R7', R7", R8, R9, R10 and R11 are independently hydrogen or lower hydrocarbyl; R12 is hydrogen; SO2 lower hydrocarbyl or COR15 ; R13 and R14 are independently lower hydrocarbyl, lower hydrocarbyloxy or a group R12 ; R15 is OR16, NR17 R18, hydrogen or lower hydrocarbyl; R16 is lower hydrocarbyl; R17 and R18 are independently hydrogen or lower hydrocarbyl; provided that when there are two or more substituents Z, they may be the same or different; and m is 0 or an integer from 1 to 5.