40106-51-2

Upstream product

• 40106-36-3 4-oxo-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 4651-91-6 3-cyano-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene 
• 623-49-4 ethyl cyanoformate 
• 4815-28-5 2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide 

Downstream Products

• 106778-67-0 4-(3-Methoxy-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-66-9 4-(2-Methoxy-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-92-1 4-Cyclohexylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-62-5 4-Phenylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-70-5 4-(3-Chloro-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-64-7 4-m-Tolylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-73-8 4-(3-Chloro-4-methyl-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-63-6 4-o-Tolylamino-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-74-9 4-(4-Fluoro-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-72-7 4-(4-Bromo-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 139059-08-8 4-(4-Nitro-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-68-1 4-(4-Methoxy-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-69-2 4-(4-Acetyl-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 
• 106778-71-6 4-(4-Chloro-phenylamino)-5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidine-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Reaction of Nitriles under Acidic Conditions. Part VI. Synthesis of Condensed 4-Chloro- and 4-Aminopyrimidines from ortho-Aminonitriles

Condensation of a nitrile with benzene, furan and thiophene ortho-aminonitriles in the presence of dry hydrogen chloride yields condensed 4-chloropyrimidines, condensed 4-aminopyrimidines or a mixture of the two condensed pyrimidines in varying proportions depending upon the nature of the nitrile and the substrate, ortho-aminonitrile.