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1H-pyrrolo[3,4-c]pyridin-3(2H)-one, also known as norharmane, is a heterocyclic compound with the molecular formula C9H7NO. It features a pyridine ring fused to a pyrrole ring and is a naturally occurring alkaloid found in plants, fungi, and animal tissues. Norharmane has been identified as a component of tobacco smoke and exhibits various biological activities, such as antioxidant, antimicrobial, and antiviral properties. It has potential applications in cancer treatment and as a neuroprotective agent, and it is known to interact with neurotransmitter systems in the brain, playing a role in the regulation of sleep and circadian rhythm.

40107-95-7

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40107-95-7 Usage

Uses

Used in Pharmaceutical Industry:
1H-pyrrolo[3,4-c]pyridin-3(2H)-one is used as a potential cancer treatment agent for its biological activities that may contribute to the inhibition of tumor growth and progression.
Used in Neuroprotection:
1H-pyrrolo[3,4-c]pyridin-3(2H)-one is used as a neuroprotective agent due to its potential to protect neurons from damage and degeneration, which could be beneficial in the treatment of neurodegenerative diseases.
Used in Sleep and Circadian Rhythm Regulation:
1H-pyrrolo[3,4-c]pyridin-3(2H)-one is used as a regulatory compound in the modulation of sleep and circadian rhythm due to its interaction with neurotransmitter systems in the brain, which may help in the treatment of sleep disorders and other conditions related to the circadian rhythm.
Used in Antimicrobial Applications:
1H-pyrrolo[3,4-c]pyridin-3(2H)-one is used as an antimicrobial agent for its ability to inhibit the growth of certain microorganisms, which can be useful in the development of new antibiotics or antifungal agents.
Used in Antioxidant Formulations:
1H-pyrrolo[3,4-c]pyridin-3(2H)-one is used as an antioxidant in various formulations to protect cells from oxidative damage, which may have applications in skincare products, dietary supplements, and other health-related products.

Check Digit Verification of cas no

The CAS Registry Mumber 40107-95-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,1,0 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40107-95:
(7*4)+(6*0)+(5*1)+(4*0)+(3*7)+(2*9)+(1*5)=77
77 % 10 = 7
So 40107-95-7 is a valid CAS Registry Number.

40107-95-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-dihydropyrrolo[3,4-c]pyridin-3-one

1.2 Other means of identification

Product number -
Other names 2-Oxo-7H-pyrrolo<3,4-c>pyridin

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40107-95-7 SDS

40107-95-7Upstream product

40107-95-7Relevant academic research and scientific papers

Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2

Galli, Ubaldina,Mesenzani, Ornella,Coppo, Camilla,Sorba, Giovanni,Canonico, Pier Luigi,Tron, Gian Cesare,Genazzani, Armando A.

, p. 58 - 66,9 (2020/07/31)

As part of an effort to identify novel selective modulators of sirtuins, we synthesized and tested several isosteres and constrained analogues of nicotinamide. Biological data suggest that compound 2 is selective for Sirt3 over Sirt1 and Sirt2.

INHIBITORS OF THE HIV INTEGRASE ENZYME

-

Page/Page column 106, (2008/06/13)

The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIV”) integrase enzyme.

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