40107-95-7 Usage
General Description
1H-pyrrolo[3,4-c]pyridin-3(2H)-one, also known as norharmane, is a chemical compound with the molecular formula C9H7NO. It is a heterocyclic compound consisting of a pyridine ring fused to a pyrrole ring. Norharmane is a naturally occurring alkaloid found in plants, fungi, and animal tissues, and it has been identified as a component of tobacco smoke. It exhibits various biological activities, including antioxidant, antimicrobial, and antiviral properties. Norharmane has also been studied for its potential use in cancer treatment and as a neuroprotective agent. Additionally, it is known to interact with neurotransmitter systems in the brain and has been implicated in the regulation of sleep and circadian rhythm.
Check Digit Verification of cas no
The CAS Registry Mumber 40107-95-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,1,0 and 7 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40107-95:
(7*4)+(6*0)+(5*1)+(4*0)+(3*7)+(2*9)+(1*5)=77
77 % 10 = 7
So 40107-95-7 is a valid CAS Registry Number.
40107-95-7Relevant articles and documents
Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2
Galli, Ubaldina,Mesenzani, Ornella,Coppo, Camilla,Sorba, Giovanni,Canonico, Pier Luigi,Tron, Gian Cesare,Genazzani, Armando A.
, p. 58 - 66,9 (2020/07/31)
As part of an effort to identify novel selective modulators of sirtuins, we synthesized and tested several isosteres and constrained analogues of nicotinamide. Biological data suggest that compound 2 is selective for Sirt3 over Sirt1 and Sirt2.
