401517-15-5

Basic information

• Product Name: 4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE
• Synonyms: AKOS B018778;4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE;ART-CHEM-BB B018778
• CAS NO: 401517-15-5
• Molecular Formula: C₄H₂ClF₃N₂
• Molecular Weight: 170.52
• Mol File: 401517-15-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 94 °C
• Boiling Point: 213.0±35.0 °C(Predicted)
• Appearance: /
• Density: 1.602±0.06 g/cm3(Predicted)
• PKA: 9.27±0.50(Predicted)
• CAS DataBase Reference: 4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE(401517-15-5)
• EPA Substance Registry System: 4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE(401517-15-5)

Safety Data

• Hazardous Substances Data: 401517-15-5(Hazardous Substances Data)

Usage

General Description

4-Chloro-3-trifluoromethyl-1H-pyrazole is a chemical compound with the molecular formula C4H2ClF3N2. It is a pyrazole derivative and contains a chloro and trifluoromethyl group attached to the pyrazole ring. 4-CHLORO-3-TRIFLUOROMETHYL-1H-PYRAZOLE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential use in the development of new materials and in organic synthesis. The compound's unique structure and reactivity make it a valuable building block for the production of diverse chemical compounds.

Upstream product

• 20154-03-4 3-(trifluoromethyl)pyrazole 

Downstream Products

• 84547-87-5 4-chloro-1H-pyrazole-3-carboxylic acid 
• 945717-10-2 (4-tert-butylbenzyl)-[2-(4-chloro-3-trifluoromethylpyrazol-1-yl)-ethyl]-amine 
• 945717-11-3 (4-tert-butylbenzyl)-[2-(4-chloro-5-trifluoromethylpyrazol-1-yl)-ethyl]-amine 
• 866638-80-4 1-(3-methyl-4-nitrobenzyl)-4-chloro-3-trifluoromethyl-1H-pyrazole 

Relevant articles and documents

ANTAGONISTS OF CHEMOKINE RECEPTORS

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.

Simple preparations of 4 and 5-iodinated pyrazoles as useful building blocks

The pyrazole nucleus has recently become a recurrent scaffold in the research fields of CropScience and oncology. We report here the preparation of an array of 4- and 5-iodinated pyrazole derivatives, such as 4-iodo-3-trifluoromethylpyrazole or ethyl 5-io

N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES

Novel benzenedicarboxamides of the formula (I) wherein X represents hydrogen, halogen atom, nitro, C1-6alkylsulfonyloxy,C1-6alkylsulfinyl, C1-6alkylsulfenyl or C1-6alkylsulfonyl, R1 represents C1-6alkyl, C1-6alkylthio-C1-6alkyl, C1-6alkylsulfinyl- C1-6alkyl or C1-6 alkylsulfonyl- C1-6alkyl, Y represents halogen or C1-6alkyl, m represents 0 or 1, A represents O, S, SO, SO2, CH2 or CH(CH3), and Q represents a 5- or 6-membered heterocyclic group that contains at least one hetero atom selected from the group consisting of N, O and S and can be optionally substituted; processes for their preparation, their intermediates and their use as insecticides.