401518-69-2Relevant academic research and scientific papers
Piperidine derivatives and drugs containing these derivatives as active ingredient
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Page/Page column 25, (2008/06/13)
Piperidine derivatives represented by formula (I) or nontoxic salts thereof (wherein symbols are defined in the description): Since the compound represented by formula (I) has a PDE4 inhibitory activity, it is useful for preventing and/or treating inflamm
Design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors
Ochiai, Hiroshi,Odagaki, Yoshihiko,Ohtani, Tazumi,Ishida, Akiharu,Kusumi, Kensuke,Kishikawa, Katuya,Yamamoto, Susumu,Takeda, Hiroshi,Obata, Takaaki,Kobayashi, Kaoru,Nakai, Hisao,Toda, Masaaki
, p. 5063 - 5078 (2007/10/03)
The mode of interaction with enzyme is hypothesized based on the SAR data. The design, synthesis, and biological evaluation of new phosphodiesterase type 4 inhibitors, which possess new templates instead of a cyclohexane ring, are described. The mode of i
