401564-45-2

Basic information

• Product Name: (2S,4S)-2-((S)-2-Cyano-pyrrolidine-1-carbonyl)-4-phenylamino-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 401564-45-2
• Molecular Weight: 384.478
• Mol File: 401564-45-2.mol

Chemical Properties

• CAS DataBase Reference: (2S,4S)-2-((S)-2-Cyano-pyrrolidine-1-carbonyl)-4-phenylamino-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4S)-2-((S)-2-Cyano-pyrrolidine-1-carbonyl)-4-phenylamino-pyrrolidine-1-carboxylic acid tert-butyl ester(401564-45-2)
• EPA Substance Registry System: (2S,4S)-2-((S)-2-Cyano-pyrrolidine-1-carbonyl)-4-phenylamino-pyrrolidine-1-carboxylic acid tert-butyl ester(401564-45-2)

Safety Data

• Hazardous Substances Data: 401564-45-2(Hazardous Substances Data)

Upstream product

• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 401564-19-0 (S)-1-((2S,4R)-1-tert-butoxycarbonyl-4-hydroxy-2-pyrrolidinylcarbonyl)-2-cyanopyrrolidine 

Relevant articles and documents

1-((S)-γ-Substituted prolyl)-(S)-2-cyanopyrrolidine as a novel series of highly potent DPP-IV inhibitors

1-(γ-Substituted prolyl)-(S)-2-cyanopyrrolidines were designed based on the predicted binding mode of the known DPP-IV inhibitor NVP-DPP728 and evaluated for their inhibitory activity. In structure-activity relationship study at the γ-position of proline,