401600-99-5Relevant academic research and scientific papers
Analogues of neuroactive polyamine wasp toxins that lack inner basic sites exhibit enhanced antagonism toward a muscle-type mammalian nicotinic acetylcholine receptor
Str?mgaard, Kristian,Brierley, Matthew J.,Andersen, Kim,Sl?k, Frank A.,Mellor, Ian R.,Usherwood, Peter N. R.,Krogsgaard-Larsen, Povl,Jaroszewski, Jerzy W.
, p. 5224 - 5234 (2007/10/03)
Philanthotoxin-433 (PhTX-433), a natural polyamine wasp toxin, is a noncompetitive antagonist of certain ionotropic receptors. Six analogues of PhTX-343 (a synthetic analogue of the natural product), in which the secondary amino groups are systematically
