401813-08-9

Upstream product

• 194724-12-4 (2R,3S)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]tetrahydrofuran-3-ol 
• 1332834-99-7 5-O-benzoyl-3-O-(4,4'-dimethoxytrityl)-1,2-dideoxy-D-ribose 
• 1332834-93-1 5-O-benzoyl-1,2-dideoxy-D-ribose 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 481067-20-3 (2R,3S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-trimethylsilanyloxy-tetrahydro-furan 
• 676164-72-0 (2R,3S)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-3-trimethylsilanyloxy-2,3-dihydro-furan 
• 50-89-5 thymidine 
• 40733-28-6 5'-tert-butyldimethylsilyloxy-2'-deoxythymidine 

Relevant academic research and scientific papers

An expedient biocatalytic procedure for abasic site precursors useful in oligonucleotide synthesis

Preparation of abasic site precursors through a divergent chemoenzymatic synthesis has been accomplished. Several biocatalysts and acylating agents were studied furnishing a practical and scalable green method useful for industrial applications. Highly re

Synthesis of 1,4-anhydro-2-deoxy-d-ribitol derivatives from thymidine

1,2-Dideoxyribose 5-O-succinate, a component of solid support employed in the synthesis of ribozymes, was synthesized from thymidine. The key step was elimination of nucleobase from 2 to afford glycal 3. A number of catalysts for this reaction were tested