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BOC-3-(2-QUINOLYL)-DL-ALA-OH is a complex chemical compound that integrates a BOC (tert-butyloxycarbonyl) protecting group, a 2-quinolyl moiety, and a DL-alanine residue. The BOC group is a common protective agent for amine groups in organic synthesis, the 2-quinolyl group contributes a heterocyclic aromatic structure, and DL-alanine is an essential alpha-amino acid involved in protein biosynthesis. BOC-3-(2-QUINOLYL)-DL-ALA-OH holds potential for various applications in organic synthesis, medicinal chemistry, and related fields due to the unique properties of its constituent groups.

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  • 401813-49-8 Structure
  • Basic information

    1. Product Name: BOC-3-(2-QUINOLYL)-DL-ALA-OH
    2. Synonyms: boc-3-(2-quinolyl)-dl-alanine
    3. CAS NO:401813-49-8
    4. Molecular Formula: C17H20N2O4
    5. Molecular Weight: 0
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 401813-49-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 505.6°C at 760 mmHg
    3. Flash Point: 259.6°C
    4. Appearance: /
    5. Density: 1.235g/cm3
    6. Vapor Pressure: 4.81E-11mmHg at 25°C
    7. Refractive Index: 1.59
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: BOC-3-(2-QUINOLYL)-DL-ALA-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: BOC-3-(2-QUINOLYL)-DL-ALA-OH(401813-49-8)
    12. EPA Substance Registry System: BOC-3-(2-QUINOLYL)-DL-ALA-OH(401813-49-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 401813-49-8(Hazardous Substances Data)

401813-49-8 Usage

Uses

Used in Organic Synthesis:
BOC-3-(2-QUINOLYL)-DL-ALA-OH is used as a protected amine intermediate for the synthesis of complex organic molecules. The BOC group shields the amine functionality, allowing for selective reactions to occur at other sites within the molecule, which is crucial for the construction of intricate molecular architectures.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, BOC-3-(2-QUINOLYL)-DL-ALA-OH serves as a building block for the development of novel pharmaceutical agents. BOC-3-(2-QUINOLYL)-DL-ALA-OH's structural elements, including the heterocyclic 2-quinolyl group and the DL-alanine residue, can be tailored to target specific biological receptors or enzymes, potentially leading to the creation of new drugs with unique mechanisms of action.
Used in Peptide Synthesis:
BOC-3-(2-QUINOLYL)-DL-ALA-OH is utilized as a key component in the synthesis of peptides and peptidomimetics. The DL-alanine residue can be incorporated into peptide sequences, while the BOC protecting group ensures that the amine group remains unreactive until the desired point in the synthesis process, facilitating the stepwise assembly of peptide chains.
Used in Heterocyclic Chemistry:
BOC-3-(2-QUINOLYL)-DL-ALA-OH is also used as a precursor in the synthesis of heterocyclic compounds, leveraging the 2-quinolyl group's aromatic and heterocyclic characteristics. The presence of this group can influence the electronic properties of the final product, making it suitable for applications in materials science and as potential pharmaceutical agents.
Used in Research and Development:
BOC-3-(2-QUINOLYL)-DL-ALA-OH is employed in research settings to explore the chemical and biological properties of novel compounds. Its unique structure allows scientists to investigate the effects of the BOC protecting group, the 2-quinolyl moiety, and the DL-alanine residue on the compound's reactivity, stability, and potential interactions with biological targets.

Check Digit Verification of cas no

The CAS Registry Mumber 401813-49-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,8,1 and 3 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 401813-49:
(8*4)+(7*0)+(6*1)+(5*8)+(4*1)+(3*3)+(2*4)+(1*9)=108
108 % 10 = 8
So 401813-49-8 is a valid CAS Registry Number.
InChI:InChI=1/C17H20N2O4/c1-17(2,3)23-16(22)19-14(15(20)21)10-12-9-8-11-6-4-5-7-13(11)18-12/h4-9,14H,10H2,1-3H3,(H,19,22)(H,20,21)

401813-49-8 Well-known Company Product Price

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  • Aldrich

  • (56918)  Boc-3-(2-quinolyl)-DL-Ala-OH  ≥95.0%

  • 401813-49-8

  • 56918-1G

  • 5,108.22CNY

  • Detail

401813-49-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Boc-3-(2-quinolyl)-DL-Ala-OH

1.2 Other means of identification

Product number -
Other names 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-quinolin-2-ylpropanoic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:401813-49-8 SDS

401813-49-8Downstream Products

401813-49-8Relevant articles and documents

Boronic ester and acid compounds, synthesis and uses

-

, (2008/06/13)

Disclosed herein are boronic ester and acid compounds, their synthesis and uses. More specifically, disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds.

BORONIC ESTER AND ACID COMPOUNDS

-

, (2008/06/13)

Disclosed herein is a method for reducing the rate of degradation of proteins in an animal comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.

Intercalator amino acids: Synthesis of heteroaryl alanines

Krippner,Harding

, p. 1793 - 1804 (2007/10/02)

Stereoselective alkylation of (S)-(-)-2-t-butyl-1-t-butyloxycarbonyl-3-methyl-4-imidazolinone with 2-chloromethylquinoline, 2-chloromethylquinoxaline and 5-chloromethyl-1,10-phenanthroline, followed by hydrolysis, afforded the corresponding (S)-(+)-α-amino acids with high enantiomeric excess.

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