401892-84-0

Usage

Uses

4-(Pentafluorothio)benzaldehyde is used as pharmaceutical intermediate.

InChI:InChI=1/C7H5F5OS/c8-14(9,10,11,12)7-3-1-6(5-13)2-4-7/h1-5H

Upstream product

• 2613-27-6 1-nitro-4-(pentafluorosulfanyl)benzene 
• 1179906-82-1 N-methoxy-N-methyl-4-(pentafluoro-λ⁶-sulfanyl)benzamide 
• 832-32-6 4-(pentafluoro-λ⁶-sulphanyl)benzoic acid 
• 201230-82-2 carbon monoxide 
• 286947-68-0 pentafluoro(4-iodophenyl)-λ⁶-sulfane 
• 2993-24-0 4-(pentafluorosulfanyl)aniline 
• 2591-86-8 N-Formylpiperidine 
• 774-93-6 1-bromo-4-pentafluorosulfanylbenzene 

Downstream Products

• 832-32-6 4-(pentafluoro-λ⁶-sulphanyl)benzoic acid 
• 1146695-80-8 4-methyl-5-(4-(pentafluorothio)phenyl)oxazole 
• 1179906-85-4 methyl 2-methyl-2-{[1-(4-pentafluorosulfanylphenyl)methylidene]-amino}propionate 
• 1179906-88-7 methyl 2-methyl-2-(4-pentafluorosulfanylbenzylamino)propionate 
• 1179905-96-4 3-(3,4-difluorophenyl)-5,5-dimethyl-1-(4-pentafluorosulfanylbenzyl)-imidazolidine-2,4-dione 
• 1046446-99-4 pentafluoro(4-vinylphenyl)-λ⁶-sulfane 
• 773872-73-4 [4-(pentafluoro-λ⁶-sulfanyl)phenyl]methanol 

Relevant academic research and scientific papers

Novel phenyl-substituted imidazolidines, process for preparation thereof, medicaments comprising said compounds and use thereof

The invention relates to compounds of formula (I) wherein the groups have stated meanings, and to their physiologically compatible salts. Said compounds are suitable, for example, as anti-obesity drugs and for treating cardiometabolic syndrome.

TRPV1 ANTAGONISTS

Compounds of formula (I) wherein R1, R2, R4, and W are defined in the description are TRPV 1 antagonists with CNS penetration. Compositions comprising such compounds and methods for treating conditions and disorders using

Synthesis and characterisation of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives. X-ray structure of 3-SF5-C6H4-COOH

The high yield synthesis of 3- and 4-(pentafluorosulfanyl)benzoic acid derivatives is described starting from the NO2-derivatives, which are reduced to the corresponding anilines. Then the NH2- group is converted to bromide and subsequently to the HC{double bond, long}O moiety. The benzaldeydes are then oxidised to the corresponding benzoic acids. The X-ray structure of 3-SF5-C6H4-COOH is also reported.

Liquid crystals based on hypervalent sulfur fluorides: Pentafluorosulfuranyl as polar terminal group

The somewhat 'exotic' pentafluorosulfuranyl functionality is one of the strongest electron-withdrawing groups with a purely inductive effect owing to its chemical stability and the resulting high dipole moment of its aromatic derivatives, this group was crucial to the design and synthesis of a new class of highly polar liquid crystals (such as 1) for application in active matrix displays. A computational model was developed with the aim to understand and predict the electrooptic properties of liquid crystals based on hypervalent sulfur fluorides.