401895-86-1Relevant academic research and scientific papers
Synthetic studies on the BCDF ring system of ristocetin A via ruthenium-promoted SNAr reaction
Pearson, Anthony J.,Zigmantas, Sarunas
, p. 8765 - 8768 (2001)
Ruthenium-promoted intramolecular SNAr reaction has allowed the construction of the 16-membered BCD model macrocycle of ristocetin A that incorporates the required arylserine residue as the C ring, and includes a fully functionalized F ring.
Structure-guided evolution of a ketoreductase for efficient and stereoselective bioreduction of bulky α-amino β-keto esters
Chen, Liuqing,Chen, Shaoxin,Feng, Meiqing,Ni, Guowei,Tang, Jiawei,Wang, Hongyi,Yu, Jun,Yuan, Shuguang,Zhang, Fuli,Zhang, Luwen
, p. 6755 - 6769 (2021/10/25)
Ketoreductases have shown considerable potential as biocatalysts in the asymmetric synthesis of chiral alcohols. However, compared to the widely studied ketoreductases for chiral alcohols, limited knowledge is available about ketoreductases for efficient
