401909-72-6

Basic information

• Product Name: methyl 3-{3-fluoro-4-[(methanesulfony)amino]phenyl}propanoate
• Synonyms: methyl 3-{3-fluoro-4-[(methanesulfony)amino]phenyl}propanoate
• CAS NO: 401909-72-6
• Molecular Weight: 275.301
• Mol File: 401909-72-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-{3-fluoro-4-[(methanesulfony)amino]phenyl}propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-{3-fluoro-4-[(methanesulfony)amino]phenyl}propanoate(401909-72-6)
• EPA Substance Registry System: methyl 3-{3-fluoro-4-[(methanesulfony)amino]phenyl}propanoate(401909-72-6)

Safety Data

• Hazardous Substances Data: 401909-72-6(Hazardous Substances Data)

Upstream product

• 1165739-17-2 methyl (E)-3-[3-fluoro-4-(methylsulfonamido)phenyl]acrylate 

Downstream Products

• 401908-81-4 N-(4-tert-butylbenzyl)-3-[3-fluoro-4-(methylsulfonamido)phenyl]propanamide 

Relevant articles and documents

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

We have developed a new class of diarylalkyl amides as novel TRPV1 antagonists. They exhibited potent 45Ca2+ uptake inhibitions in rat DRG neuron. In particular, the amide 59 was identified as a potent antagonist with IC50 of 57 nM. The synthesis and structure-activity relationship of the diarylalkyl amides are also described.