401915-55-7

Basic information

• Product Name: (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide
• Synonyms: fmoc-β-homogln(trt)-oh;Fmoc--HoGln(Trt)-OH;Fmoc-b-HoGln(Trt)-OH;(S)-3-(Fmoc-amino)-N-trityl-adipic acid 6-amide, Nβ-Fmoc-Nε-trityl-L-homoglutamine;FMOC-B-HOMO-GLN(TRT)-OH;Nβ-Fmoc-Nε-trityl-L-homoglutamine;Fmoc-D-beta-HoGln(Trt)-OH;FMoc-L-b-hoMoGln(trt)-OH
• CAS NO: 401915-55-7
• Molecular Formula: C₄₀H₃₆N₂O₅
• Molecular Weight: 624.733
• Product Categories: Unusual Amino Acids
• Mol File: 401915-55-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 113-117℃
• Boiling Point: 878.6±65.0 °C(Predicted)
• Appearance: /
• Density: 1.243±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.32±0.10(Predicted)
• BRN: 9601212
• CAS DataBase Reference: (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide(401915-55-7)
• EPA Substance Registry System: (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide(401915-55-7)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 401915-55-7(Hazardous Substances Data)

Usage

Description

(s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide is a chemical compound that features a trityl-protected amine group connected to an adipic acid backbone. (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide incorporates the fmoc-amino group, a standard protecting group in peptide synthesis, and the trityl group, which is utilized for shielding hydroxyl groups in organic synthesis. The adipic acid backbone serves as a spacer arm, allowing the attachment of the amino group to a solid support like resin during peptide synthesis. The amide bond between the adipic acid and the fmoc-amino-trityl group imparts stability and rigidity to the molecule, rendering it a valuable reagent in the fields of peptide synthesis and organic chemistry.

Uses

Used in Peptide Synthesis:
(s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide is used as a protecting group in peptide synthesis for the amine group. It ensures the selective protection of the amine during the synthesis process, preventing unwanted side reactions and facilitating the stepwise assembly of peptide chains.
Used in Organic Chemistry:
In the field of organic chemistry, (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide is used as a protecting group for hydroxyl groups. The trityl group provides a stable and easily removable protection, allowing chemists to carry out reactions on other functional groups without affecting the hydroxyl groups.
Used in Drug Development:
(s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide can be employed in the development of pharmaceutical compounds, particularly in the synthesis of peptide-based drugs. Its role in peptide synthesis allows for the creation of complex and biologically active molecules with potential therapeutic applications.
Used in Research and Development:
In the research and development sector, (s)-3-(fmoc-amino)-n-trityl-adipic acid 6-amide is utilized for the synthesis and study of novel compounds with potential applications in various industries, including pharmaceuticals, materials science, and biotechnology. Its versatility as a protecting group and its stability make it a valuable tool for exploring new chemical reactions and syntheses.

Upstream product

• 132327-80-1 Fmoc-L-Gln(Trt)-OH 

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