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FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is a synthetic derivative of the amino acid leucine, featuring an FMOC (9-fluorenylmethyloxycarbonyl) protective group and a tert-butylphenyl moiety. FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID serves as a crucial building block in the synthesis of peptides and peptidomimetics, playing a significant role in research and pharmaceutical development. The FMOC group masks the amine function, facilitating selective deprotection and coupling reactions in peptide synthesis, while the tert-butylphenyl group introduces steric hindrance, potentially enhancing the stability and bioavailability of the synthesized peptides. These attributes render FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID an indispensable tool in the creation of biologically active peptides and potential drug candidates.

401916-49-2

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401916-49-2 Usage

Uses

Used in Pharmaceutical Research and Development:
FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is used as a key building block for the synthesis of peptides and peptidomimetics, which are essential for the development of new drugs and therapeutic agents. FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID's unique structure allows for the creation of peptides with enhanced stability and bioavailability, making it a valuable asset in the pharmaceutical industry.
Used in Peptide Synthesis:
In the field of organic chemistry and peptide synthesis, FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is utilized as a protected amino acid, enabling selective deprotection and coupling reactions. This selective process is crucial for the stepwise assembly of complex peptide sequences, ensuring the precise construction of biologically active molecules.
Used in the Development of Biologically Active Peptides:
FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is employed as a component in the design and synthesis of biologically active peptides. The introduction of the tert-butylphenyl group can improve the pharmacokinetic properties of the peptides, such as their stability and absorption in the body, which is vital for their therapeutic effectiveness.
Used in Academia for Research:
In academic research settings, FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is used as a model compound to study the effects of structural modifications on peptide properties. Researchers use FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID to explore the relationship between peptide structure and function, advancing the understanding of peptide-based drug design and development.

Check Digit Verification of cas no

The CAS Registry Mumber 401916-49-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,9,1 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 401916-49:
(8*4)+(7*0)+(6*1)+(5*9)+(4*1)+(3*6)+(2*4)+(1*9)=122
122 % 10 = 2
So 401916-49-2 is a valid CAS Registry Number.
InChI:InChI=1/C29H31NO4/c1-29(2,3)20-14-12-19(13-15-20)16-21(17-27(31)32)30-28(33)34-18-26-24-10-6-4-8-22(24)23-9-5-7-11-25(23)26/h4-15,21,26H,16-18H2,1-3H3,(H,30,33)(H,31,32)/t21-/m0/s1

401916-49-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (2R)-3-amino-4-(4-tert-butylphenyl)-2-(9H-fluoren-9-ylmethoxycarbonyl)butanoic acid

1.2 Other means of identification

Product number -
Other names Benzenebutanoicacid,4-(1,1-dimethylethyl)-b-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-,(bR)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:401916-49-2 SDS

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