401916-49-2

Basic information

• Product Name: FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID
• Synonyms: FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)BUTANOIC ACID;FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID;FMOC-D-BETA-HOPHE(4-TBU)-OH;FMOC-D-PHE(4-TBU)-(C*CH2)OH;RARECHEM AK PT F134;(R)-N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID;Fmoc-D-b-HoPhe(4-tBu)-OH;(9H-Fluoren-9-yl)MethOxy]Carbonyl (R)-3-Amino-4-(4-tert-butyl-phenyl)-butyric acid
• CAS NO: 401916-49-2
• Molecular Formula: C29H31NO4
• Molecular Weight: 457.56
• Product Categories: 3-Amino-4-phenylbutanoic Acid Analogs;B-Amino
• Mol File: 401916-49-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 651.5°C at 760 mmHg
• Flash Point: 347.8°C
• Appearance: /
• Density: 1.183g/cm³
• Vapor Pressure: 7.35E-18mmHg at 25°C
• Refractive Index: 1.595
• CAS DataBase Reference: FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID(401916-49-2)
• EPA Substance Registry System: FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID(401916-49-2)

Safety Data

• Hazardous Substances Data: 401916-49-2(Hazardous Substances Data)

Usage

General Description

The chemical compound FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID is a derivative of the amino acid leucine, with an added FMOC (9-fluorenylmethyloxycarbonyl) protective group and a tert-butylphenyl group. It is commonly used as a building block in the synthesis of peptides and peptidomimetics for research and pharmaceutical purposes. The FMOC protective group is used to mask the amine group, allowing for selective deprotection and coupling reactions in peptide synthesis. The tert-butylphenyl group adds steric hindrance and can enhance the stability and bioavailability of the resulting peptides. These properties make FMOC-(R)-3-AMINO-4-(4-TERT-BUTYL-PHENYL)-BUTYRIC ACID a valuable tool in the development of biologically active peptides and drug candidates.

InChI:InChI=1/C29H31NO4/c1-29(2,3)20-14-12-19(13-15-20)16-21(17-27(31)32)30-28(33)34-18-26-24-10-6-4-8-22(24)23-9-5-7-11-25(23)26/h4-15,21,26H,16-18H2,1-3H3,(H,30,33)(H,31,32)/t21-/m0/s1