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Mercaptopolyethylene glycol monomethyl ether (PEG-thiol) is a versatile chemical compound that features a PEG backbone with an attached thiol group. This unique structure enables PEG-thiol to be readily coupled with other molecules, such as proteins, peptides, or nanoparticles, facilitating the modification of their surface properties for a range of applications.

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  • 401916-61-8 Structure
  • Basic information

    1. Product Name: Mercaptopolyethylene glycol monomethyl etherPEG-thiol
    2. Synonyms: Mercaptopolyethylene glycol monomethyl etherPEG-thiol;O-[2-(3-Mercaptopropionylamino)ethyl]-Oμ-methylpolyethylene glycol;MPEG-Thiol, average M.W. 6,000;MPEG-Thiol, average M.W. 10,000;MPEG-Thiol, average M.W. 1,000;MPEG-Thiol, average M.W. 4,000;MPEG-Thiol, average M.W. 2,000;MPEG-Thiol, average M.W. 5,000
    3. CAS NO:401916-61-8
    4. Molecular Formula: C7H18O4S
    5. Molecular Weight: 198.28042
    6. EINECS: N/A
    7. Product Categories: Materials Science;Monofunctional PEGs;Poly(ethylene glycol) and Poly(ethylene oxide);Polymer Science;Polymers;Thiol;PEG
    8. Mol File: 401916-61-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: ?20°C
    8. Solubility: N/A
    9. CAS DataBase Reference: Mercaptopolyethylene glycol monomethyl etherPEG-thiol(CAS DataBase Reference)
    10. NIST Chemistry Reference: Mercaptopolyethylene glycol monomethyl etherPEG-thiol(401916-61-8)
    11. EPA Substance Registry System: Mercaptopolyethylene glycol monomethyl etherPEG-thiol(401916-61-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 401916-61-8(Hazardous Substances Data)

401916-61-8 Usage

Uses

Used in Bioconjugation and Biofunctionalization:
PEG-thiol is used as a coupling agent for the attachment of biomolecules, such as proteins and peptides, to other molecules or surfaces. The presence of the thiol group allows for the formation of stable linkages, enhancing the functionality and stability of the resulting conjugates.
Used in Drug Delivery:
In the pharmaceutical industry, PEG-thiol is used as a component in drug delivery systems. Its ability to modify the surface properties of nanoparticles and other drug carriers can improve the solubility, bioavailability, and targeting of therapeutic agents, leading to more effective treatments.
Used in Imaging and Diagnostics:
In the medical field, PEG-thiol is employed as a modifier for imaging agents and diagnostic tools. By altering the surface properties of contrast agents or probes, PEG-thiol can enhance their visibility and specificity, improving the accuracy of diagnostic procedures.
Used in Materials Science:
In the field of materials science, PEG-thiol is used as a building block for the creation of hydrogels and polymers with tunable mechanical and chemical properties. This allows researchers to develop new materials with specific characteristics for various applications, such as tissue engineering or sensor development.

Check Digit Verification of cas no

The CAS Registry Mumber 401916-61-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,9,1 and 6 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 401916-61:
(8*4)+(7*0)+(6*1)+(5*9)+(4*1)+(3*6)+(2*6)+(1*1)=118
118 % 10 = 8
So 401916-61-8 is a valid CAS Registry Number.

401916-61-8 Well-known Company Product Price

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  • (Code)Product description
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  • Aldrich

  • (11124)  O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethyleneglycol  5,000

  • 401916-61-8

  • 11124-250MG-F

  • 1,396.98CNY

  • Detail
  • Aldrich

  • (11124)  O-[2-(3-Mercaptopropionylamino)ethyl]-O′-methylpolyethyleneglycol  5,000

  • 401916-61-8

  • 11124-1G-F

  • 4,456.53CNY

  • Detail

401916-61-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methoxyethanol,2-(2-sulfanylethoxy)ethanol

1.2 Other means of identification

Product number -
Other names PEG-thiol `Mercaptopolyethylene glycol monomethyl ether

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:401916-61-8 SDS

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