402-42-6

Basic information

• Product Name: 4-FLUOROBENZOTRICHLORIDE
• Synonyms: 4-FLUOROBENZOTRICHLORIDE;4-Fluoro-alpha,,-trichlorotoluene;4-Fluoro-alpha,alpha,alpha-trichlorotoluene;Benzene,1-fluoro-4-(trichloromethyl)-;p-Fluorobenzotrichloride;p-fluoro-alpha,alpha,alpha-trichlorotoluene;4-fluoro-à,à,à-trichlorotoluene;4-Fluorobenzotrichloride 99%
• CAS NO: 402-42-6
• Molecular Formula: C₇H₄Cl₃F
• Molecular Weight: 213.46
• EINECS: 206-942-0
• Mol File: 402-42-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 76 C
• Flash Point: 95.9 °C
• Appearance: /
• Density: 1,425 g/cm
• Refractive Index: 1.534
• Storage Temp.: 2-8°C
• BRN: 2208417
• CAS DataBase Reference: 4-FLUOROBENZOTRICHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-FLUOROBENZOTRICHLORIDE(402-42-6)
• EPA Substance Registry System: 4-FLUOROBENZOTRICHLORIDE(402-42-6)

Safety Data

• Hazard Codes: Xi
• Statements: 20/22-36/37/38
• Safety Statements: 26-36/37/39-27
• RIDADR: 2810
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 402-42-6(Hazardous Substances Data)

Usage

General Description

4-Fluorobenzotrichloride is a chemical compound that is primarily used as an intermediate in the production of pharmaceuticals and other organic compounds. It is a derivative of benzotrifluoride and contains a fluorine atom and three chlorine atoms attached to a benzene ring. 4-FLUOROBENZOTRICHLORIDE is known for its reactivity and ability to undergo various chemical reactions, including nucleophilic substitution and chlorination. It is considered a hazardous substance due to its ability to cause irritation to the skin, eyes, and respiratory system upon contact. 4-Fluorobenzotrichloride is typically handled and stored with caution in a controlled laboratory or industrial setting.

InChI:InChI=1/C7H4Cl3F/c8-7(9,10)5-1-3-6(11)4-2-5/h1-4H

Upstream product

• 352-32-9 p-fluorotoluene 
• 402-44-8 4-Fluorobenzotrifluoride 
• 4755-77-5 Ethyl oxalyl chloride 
• 462-06-6 fluorobenzene 
• 352-11-4 1-chloromethyl-4-fluorobenzene 

Downstream Products

• 456-19-9 4-fluorobenzal chloride 
• 26167-19-1 <4-Fluor-phenyl>-tris-trimethylsilyl-methan 
• 87996-56-3 trifluoromethoxy-4 fluoro-4' benzophenone 
• 59396-50-8 4-fluoro-3-methylphenyl 4-fluorophenyl ketone 
• 1334834-17-1 3,3',5,5'-tetramethyl-4''-fluorobenzaurin 
• 1334834-19-3 3,3'-dimethyl-4''-fluorobenzaurin 
• 345-92-6 4,4'-Difluorobenzophenone 
• 403-43-0 4-fluorobenzoyl chloride 
• 1629-26-1 2-(4-fluorophenyl)-benzothiazole 
• 443672-17-1 3-(4-fluorophenyl)-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide 
• 1208259-07-7 2-(4-fluorophenyl)-quinazoline 
• 352-32-9 p-fluorotoluene 
• 565-04-8 α,α,α',α'-tetrachloro-4,4'-difluoro-bibenzyl 
• 400-94-2 4-fluoro-3-nitrobenzoyl chloride 

Relevant articles and documents

Synthesis of N,N′-Dialkylated Cyclohexane-1,2-diamines and Their Application as Asymmetric Ligands and Organocatalysts for the Synthesis of Alcohols

A series of N,N′-dialkylated derivatives of (1R,2R)-cyclohexane-1,2-diamine were synthesized, and a new approach to the one-pot preparation of this type of amine was demonstrated. The prepared diamines were used as organocatalysts for the two-step synthesis of α-hydroxy γ-keto esters from arenes, chlorooxoacetates, and ketones; they were also used as chiral ligands for Meervein-Ponndorf-Verley reductions and Henry reactions.

Preparation process of fluorine substituted aromatic compound

A preparation process of a fluorine substituted aromatic compound comprising reacting an alkali metal or alkali earth metal salt of an aromatic compound having a hydroxy group with an organic fluorinating agent is disclosed. As a representative fluorinating agent, a bis-dialkylamino-difluoromethane compound, for example, 2,2′-difluoro-1,3-dimethylimidazolidine, is exemplified. According to the process, an industrially useful fluorinated aromatic compound, for example, a fluorobenzene, a fluorine substituted benzophenone, a fluorine substituted diarylsulfone can be prepared with ease in economy without specific equipment.