Welcome to LookChem.com Sign In|Join Free
  • or
4-Ethoxybenzenesulfonyl fluoride, also known as 4-ethoxyphenylmethylsulfonyl fluoride or AEBSF, is a potent and irreversible serine protease inhibitor commonly used in biochemical research and molecular biology applications. This chemical compound has the molecular formula C9H11FO3S and a molecular weight of 216.25 g/mol. It is a colorless to pale yellow crystalline solid that is soluble in water, methanol, and acetonitrile. AEBSF is particularly effective in inhibiting serine proteases, such as trypsin, chymotrypsin, and subtilisin, by forming a covalent bond with the active site serine residue, thus preventing further proteolysis. It is widely used in various applications, including the stabilization of proteins, the prevention of proteolysis during sample preparation, and the study of enzyme kinetics. Due to its high reactivity and specificity, AEBSF is a valuable tool in the field of biochemistry and molecular biology.

402-56-2

Post Buying Request

402-56-2 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

402-56-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 402-56-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,0 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 402-56:
(5*4)+(4*0)+(3*2)+(2*5)+(1*6)=42
42 % 10 = 2
So 402-56-2 is a valid CAS Registry Number.

402-56-2Upstream product

402-56-2Downstream Products

402-56-2Relevant academic research and scientific papers

Arenesulfonyl Fluoride Synthesis via Copper-Catalyzed Fluorosulfonylation of Arenediazonium Salts

Liu, Yongan,Yu, Donghai,Guo, Yong,Xiao, Ji-Chang,Chen, Qing-Yun,Liu, Chao

supporting information, p. 2281 - 2286 (2020/03/13)

We report herein a general and practical copper-catalyzed fluorosulfonylation reaction of a wide range of abundant arenediazonium salts to smoothly prepare various arenesulfonyl fluorides using the 1,4-diazabicyclo[2.2.2]octane-bis(sulfur dioxide) adduct as a convenient sulfonyl source in combination with KHF2 as an ideal fluorine source and without the need for additional oxidants. Interestingly, the electronic character of the arene ring in the starting arenediazonium salts has a significant impact on the reaction mechanistic pathway.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 402-56-2