40217-50-3Relevant academic research and scientific papers
SYNTHESIS OF NAUCLEFINE, ANGUSTIDINE, ANGUSTINE, (+/-)-13b,14-DIHYDROANGUSTINE AND NAULAFINE
Repke, David B.,Jahangir,Clark, Robin D.,Nelson, Janis T.,MacLean, David B.
, p. 2541 - 2550 (2007/10/02)
The lithio derivatives of 3-cyano-4-methylpyridines and 6,7-dihydro-5H-2-pyridine-4-carbonitrile react with 2,9-bis-(trimethylsilyl)-3,4-dihydropyridoindolium trifluoromethanesulfonate to form cyclic amidines which, upon hydrolysis and oxidation, produce the title alkaloids.
Synthesis of Nauclefine, Angustidine, Angustine, and (+/-)-13b,14-Dihydroangustine
Repke, David B.,Jahangir,Clark, Robin D.,MacLean, David B.
, p. 439 - 440 (2007/10/02)
2,9-Bis-(trimethylsilyl)-3,4-dihydropyridoindolium trifluoromethanesulphonate reacts with the lithio derivatives of 3-cyano-4-methylpyridines to generate pentacyclic amidines which, upon hydrolysis and oxidation, produce nauclefine, angustine, and angustidine.
