40233-33-8Relevant academic research and scientific papers
PROCESS FOR THE PREPARATION OF BENZIMIDAZOLES
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Page/Page column 7, (2011/01/12)
Substituted benzimidazoles of formula (I), wherein R1 and R2 independently are hydrogen, C1-6 alkyl or C3-6 cycloalkyl and R3 is cyano or carboxy, are prepared in a multistep synthesis starting from Ν-acyl-4-halo- anilines of formula (II), wherein R1 and R2 are as defined above and X is chlorine or bromine.
PROCESS AND INTERMEDIATES FOR THE PREPARATION OF BENZIMIDAZOLECARBOXYLIC ACIDS
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Page/Page column 8, (2011/01/12)
Substituted benzimidazolecarboxylic acids of formula (I), wherein R1 and R2 independently are hydrogen, C1-6 alkyl or C3-6 cycloalkyl, are prepared in a four-step synthesis starting from N-acyl-4-haloanilines of formula (II), wherein R1 is as defined above, R3 is C1-4 alkyl and X is chlorine or bromine.
