2''-Deoxyadenosine 5''-diphosphate trisodium salt (DADP-Na3) is a nucleotide that plays a crucial role in various biochemical processes. It is a deoxyribonucleotide, which is a component of DNA, and is involved in the synthesis of deoxyadenylate oligonucleotides. DADP-Na3 is also used as an inhibitor in certain enzymatic reactions and as an alternative substrate or inhibitor for studying the specificity of ATPase and DNA and RNA polymerases.
402491-35-4
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Basic information
- Product Name: 2''-DEOXYADENOSINE 5''-DIPHOSPHATE TRISODIUM SALT (DADP-NA3)
- Synonyms: 2''-DEOXYADENOSINE-5''-DIPHOSPHATE, TRISODIUM SALT (DADP.NA3);Adenosine5'-(trihydrogen diphosphate), 2'-deoxy-, trisodium salt (9CI)
- CAS NO:402491-35-4
- Molecular Formula: C10H12N5O9P2.3Na
- Molecular Weight: 477.149
- EINECS: N/A
- Product Categories: N/A
- Mol File: 402491-35-4.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- Water Solubility: Soluble in water.
- CAS DataBase Reference: 2''-DEOXYADENOSINE 5''-DIPHOSPHATE TRISODIUM SALT (DADP-NA3)(CAS DataBase Reference)
- NIST Chemistry Reference: 2''-DEOXYADENOSINE 5''-DIPHOSPHATE TRISODIUM SALT (DADP-NA3)(402491-35-4)
- EPA Substance Registry System: 2''-DEOXYADENOSINE 5''-DIPHOSPHATE TRISODIUM SALT (DADP-NA3)(402491-35-4)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 402491-35-4(Hazardous Substances Data)
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402491-35-4 Usage
Uses
Used in Biochemical Research:2''-Deoxyadenosine 5''-diphosphate trisodium salt (DADP-Na3) is used as a substrate for the synthesis of deoxyadenylate oligonucleotides with enzymes such as polynucleotide phosphorylase from Escherichia coli. This application is essential for studying the mechanisms of DNA and RNA synthesis and understanding the role of nucleotides in these processes.
Used in Enzyme Inhibition:
DADP-Na3 is used as an inhibitor of bacterial poly(A) polymerase, an enzyme involved in the addition of poly(A) tails to mRNA molecules. This application is important for studying the regulation of gene expression and the role of poly(A) polymerase in bacterial systems.
Used in ATPase and Polymerase Specificity Studies:
DeoxyADP may be used as an alternative substrate or inhibitor for studies of ATPase and DNA and RNA polymerase specificity. This application helps researchers understand the mechanisms of these enzymes and their interactions with different substrates, which can be crucial for developing new therapeutic strategies and understanding the molecular basis of various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 402491-35-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,2,4,9 and 1 respectively; the second part has 2 digits, 3 and 5 respectively.Calculate Digit Verification of CAS Registry Number 402491-35:
(8*4)+(7*0)+(6*2)+(5*4)+(4*9)+(3*1)+(2*3)+(1*5)=114
114 % 10 = 4
So 402491-35-4 is a valid CAS Registry Number.
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2''-DEOXYADENOSINE 5''-DIPHOSPHATE TRISODIUM SALT (DADP-NA3)
