402728-74-9

Upstream product

• 762-72-1 allyl-trimethyl-silane 
• 75-90-1 2,2,2-Trifluoroacetaldehyde 
• 356762-89-5 N-(1,1-diphenyl-3-butenyl)amine 

Downstream Products

• 627533-03-3 benzyl N-(7-octenyl)-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 627533-02-2 benzyl N-(5-hexenyl)-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 627533-01-1 benzyl N-(4-pentenyl)-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 627533-10-2 benzyl N-(2-butynyl)-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 627533-09-9 benzyl N-(2-propynyl)-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 627533-00-0 benzyl N-allyl-N-[1-(trifluoromethyl)-3-butenyl]carbamate 
• 509093-24-7 4-(benzyloxycarbonyl)amino-5,5,5-trifluoropent-1-ene 

Relevant academic research and scientific papers

Lewis acidic FeCl3 promoted 2-aza-Cope rearrangement to afford α-substituted homoallylamines in dimethyl carbonate

The iron(iii)-catalyzed efficient strategy for the synthesis of α-substituted homoallylamines was accomplished via a cationic 2-aza-Cope rearrangement of aldimines, generated in situ by condensation of commercially available aldehydes and easily synthesizable 1,1-diphenylhomoallylamines. This reaction features a broad substrate scope with high yields and is conducted in an eco-friendly solvent, i.e. dimethyl carbonate.

Reactivity of stable trifluoroacetaldehyde hemiaminals. 2. Generation and synthetic potentialities of fluorinated iminiums

Under Lewis acid activation, hemiaminals of trifluoroacetaldehyde and related (fluoroalkyl)-aldehydes generate iminium species that can react with various nucleophiles to provide fluorinated amines.