402767-63-9

Upstream product

• 402767-55-9 5-(4-carboxyphenyl)-2-thiophenecarbonitrile 
• 150-13-0 4-amino-benzoic acid 
• 1003-31-2 thiophene-2-carbonitrile 
• 174658-22-1 4-amino-3-mercaptobenzonitrile 
• 402767-59-3 2-(4-chlorocarbonylphenyl)-5-thiophenecarbonitrile 

Downstream Products

• 402767-77-5 2-{4-[6-(N-isopropylamidino)benzothiazol-2-yl]phenyl}-5-(N-isopropylamidino)thiophene 
• 402767-68-4 2-{4-[6-(imidazolin-2-yl)benzothiazol-2-yl]phenyl}-5-(imidazolin-2-yl)thiophene 

Relevant academic research and scientific papers

Synthesis of BIS-substituted amidinobenzothiazoles as potential anti-HIV agents

In the multistep syntheses of the title compounds we obtained some new cyano-substituted heterocycles (1a, 1b, 2a, and 2b) as intermediates. Starting from dinitriles (2a and 2b) as well as from two formerly prepared dinitriles, substituted bisamidines (3a, 3b, 5a, 5b, 7a, and 7b) and amidino dihydrochlorides (4a, 4b, 6a, 6b, 8a, 8b, 9a, and 9b) have been synthesized.