40288-50-4

Upstream product

• 622-59-3 1-isothiocyanato-4-methylbenzene 

Downstream Products

• 40288-30-0 4-p-tolyl-5-p-tolylimino-[1,2,4]dithiazolidine-3-thione 
• 40288-31-1 4-phenyl-5-p-tolylimino-[1,2,4]dithiazolidine-3-thione 

Relevant academic research and scientific papers

Synthesis and biological evaluation of S-maltosylated 1,2,4- thiadiazoline derivatives against human pathogens

A series of new 4-aryl-5-p-tolylimino-3-S-hepta-O-acetyl maltosyl-1,2,4- thiadiazolines were synthesized by the interaction of N-p-tolyl-S-chloro isothiocarbamoyl chloride with S-hepta-O-acetyl maltosyl-1-aryl isothiocarbamides. These compounds were scree

First non-ATP competitive glycogen synthase kinase 3 β (GSK-3β) inhibitors: Thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

Glycogen synthase kinase 3 β (GSK-3β) has a central role in Alzheimer′s disease (AD). Selective inhibitors which avoid τ hyperphosphorylation may represent an effective therapeutical approach to the AD pharmacotherapy and other neurodegenerative disorders