402945-80-6Relevant academic research and scientific papers
Catalyst free, regioselective one-pot three-component synthesis of thiazol-2-imine derivatives in ionic liquid
Santosh Kumar,Pushpa Ragini,Meshram
, p. 5974 - 5978 (2013/10/22)
A one-pot three-component approach for the synthesis of thiazol-2-imines has been described by the reaction of amine, phenyl isothiocyanate and β-nitroacrylate in [Hbim]BF4 ionic liquid. The method is applicable for aromatic, benzylic, aliphatic and cyclic amines. Reusable reaction media, regioselectivity, mild reaction condition, catalyst free and high yield of products are the salient features of this protocol.
Solvent-free synthesis of functionalized 2,3-dihydrothiazoles from isothiocyanates, primary alkylamines, and 2-chloro-1,3-dicarbonyl compounds
Yavari, Issa,Sanaeishoar, Tayebeh,Ghazvini, Maryam,Iravani, Nasir
experimental part, p. 169 - 176 (2010/11/17)
A simple one-pot synthesis of 3-alkyl-4-methyl-2-phenylimino-2,3- dihydrothiazoles from the reaction of phenylisothiocyanate, primary alkylamines and 2-chloro-1,3-dicarbonyl compounds under solvent-free conditions is described.
