40313-66-4

Usage

Uses

Used in Chemical Synthesis:
[5-(2-Chloro-phenyl)-furan-2-yl]-methanol is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows for further functionalization and reaction with other molecules, making it a valuable building block in the creation of complex molecules.
Used in Pharmaceutical Industry:
[5-(2-Chloro-phenyl)-furan-2-yl]-methanol is used as a potential pharmaceutical candidate for the development of new drugs. Its structural features may provide opportunities for the design of novel therapeutic agents, particularly in the areas of medicinal chemistry and drug discovery.
Used in Material Science:
[5-(2-Chloro-phenyl)-furan-2-yl]-methanol is used as a component in the development of new materials with specific properties. Its incorporation into polymers or other materials may lead to the creation of materials with unique characteristics, such as improved stability, reactivity, or selectivity.
Used in Research and Development:
[5-(2-Chloro-phenyl)-furan-2-yl]-methanol is used as a research compound for studying its chemical properties, reactivity, and potential applications. Its unique structure provides a basis for understanding the behavior of organochlorine compounds and their interactions with other molecules, which can be valuable in advancing scientific knowledge in various fields.

InChI:InChI=1/C11H9ClO2/c12-10-4-2-1-3-9(10)11-6-5-8(7-13)14-11/h1-6,13H,7H2

Upstream product

• 34035-04-6 5-(2-chlorophenyl)furan-2-carbaldehyde 
• 98-01-1 furfural 
• 95-51-2 o-chloroaniline 
• 41019-43-6 5-(2-chlorophenyl)-2-furoic acid 
• 88-14-2 2-furanoic acid 
• 61941-89-7 5-(2-chlorophenyl)-2-furoyl chloride 

Downstream Products

• 1018662-98-0 C₁₁H₈Cl₂O 
• 58110-39-7 (E)-3-(5-(2-Chlorophenyl)furan-2-yl)acrylic acid 
• 1032338-19-4 C₁₉H₁₂Cl₃NO₄ 
• 1032337-96-4 C₁₉H₁₂ClF₂NO₄ 

Relevant academic research and scientific papers

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

2-amino-3-(5-phenylfuran-2-yl)propionic acids and 5-phenylfuran-2-ylacrylic acids are novel substrates of phenylalanine ammonia-lyase

Both racemic 2-amino-3-(5-phenylfuran-2-yl)propionic acids and 5-phenylfuran-2-ylacrylic acids were synthesized and spectroscopically characterized (UV, EI-MS, 1H-NMR and 13C-NMR). The phenyl group of the 5-phenylfuranyl residue carried no (rac-la) para-Br (rac-lb) or Cl para or ortho (rac-lc, d) substituents. The novel furanylalanines were used as substrates of recombinant phenylalanine ammonia-lyase (PAL). When 50% of the racemic 5-phenylfuranylalanines were converted into the corresponding acrylates, the D-enantiomers of the substrates could be isolated. The L-enantiomers could be prepared from the substituted acrylates when the PAL reaction was reversed in the presence of 6 M ammonia at pH 10. The Japan Institute of Heterocyclic Chemistry.

Synthesis and fungicidal activity of aryl carbamic acid-5-aryl-2- furanmethyl ester

Chitin, a major structural component of insect cuticle and fungus cell wall but absent in plants and vertebrates, is regarded as a safe and selective target for pest control agents. Chitin synthesis inhibitors (CSIs) have been well-known as insect growth regulators (IGRs) but rarely found as fungicides in agriculture. To find novel CSIs with good activity, benzoylphenylurea, a typical kind of CSIs, was chosen as the lead compound and 26 novel aryl carbamic acid-5-aryl-2-furanmethyl esters were designed by converting the urea linkages of benzoylphenylureas to carbamic acid esters and changing the aniline parts into furanmethyl groups. The title compounds were synthesized and their structures confirmed by IR, 1H NMR, and elemental analysis. Preliminary insecticidal and fungicidal bioassays were carried out. The results indicated that the title compounds had no insecticidal effect on Culex pipiens pallens and Plutella xylostella Linnaeus, but most compounds exhibited good fungicidal activities against Corynespora cassiicola, Thanatephorus cucumeris, Botrytis cinerea, and Fusarium oxysporum. In particular, compounds V-4, V-6, V-7, and V-8 showed better activities against the four strains than those of the commercialized fungicides. The morphologic result suggested that compound V-21 had disturbed the cell wall formation of C. cassiicola. The results indicated that modification on the urea linkage of benzoylphenylurea was an effective way to discover new candidates for fungicides.