40313-66-4

Basic information

• Product Name: [5-(2-CHLORO-PHENYL)-FURAN-2-YL]-METHANOL
• Synonyms: RARECHEM AL BD 0772;AKOS BB-8301;[5-(2-CHLOROPHENYL)-2-FURYL]METHANOL;[5-(2-CHLORO-PHENYL)-FURAN-2-YL]-METHANOL;ASISCHEM B52520;ART-CHEM-BB B025315;2-(2-Chlorophenyl)-5-(hydroxymethyl)furan;[5-(2-Chlorophenyl)fur-2-yl]methanol
• CAS NO: 40313-66-4
• Molecular Formula: C₁₁H₉ClO₂
• Molecular Weight: 208.64
• Mol File: 40313-66-4.mol
• Article Data: 3

Chemical Properties

• Melting Point: 53-55°C
• Boiling Point: 315.3 °C at 760 mmHg
• Flash Point: 144.5 °C
• Appearance: /
• Density: 1.277 g/cm³
• Vapor Pressure: 0.000187mmHg at 25°C
• Refractive Index: 1.581
• CAS DataBase Reference: [5-(2-CHLORO-PHENYL)-FURAN-2-YL]-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [5-(2-CHLORO-PHENYL)-FURAN-2-YL]-METHANOL(40313-66-4)
• EPA Substance Registry System: [5-(2-CHLORO-PHENYL)-FURAN-2-YL]-METHANOL(40313-66-4)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 40313-66-4(Hazardous Substances Data)

Usage

General Description

"[5-(2-Chloro-phenyl)-furan-2-yl]-methanol" is a chemical compound that falls under the category of organochlorine compounds. This group of chemicals is characterized by having at least one covalently bonded chlorine atom. The compound intrinsically has a furanic ring, a structural component typical of furans, with a 5 (2-chloro-phenyl) substitution and a methanol group attached to it. Furan is a heterocyclic compound and the term ‘phenyl’ suggests the presence of a phenyl group, a functional aromatic ring derivative of benzene. This particular compound, due to its structural attributes, might have specific chemical properties and reactivities, and its potential uses or roles in various industrial or chemical areas should be studied under experimental conditions.

InChI:InChI=1/C11H9ClO2/c12-10-4-2-1-3-9(10)11-6-5-8(7-13)14-11/h1-6,13H,7H2

Upstream product

• 61941-89-7 5-(2-chlorophenyl)-2-furoyl chloride 
• 88-14-2 2-furanoic acid 
• 41019-43-6 5-(2-chlorophenyl)-2-furoic acid 
• 95-51-2 o-chloroaniline 
• 98-01-1 furfural 
• 34035-04-6 5-(2-chlorophenyl)furan-2-carbaldehyde 

Downstream Products

• 1018662-98-0 C₁₁H₈Cl₂O 
• 58110-39-7 (E)-3-(5-(2-Chlorophenyl)furan-2-yl)acrylic acid 
• 1032338-19-4 C₁₉H₁₂Cl₃NO₄ 
• 1032337-96-4 C₁₉H₁₂ClF₂NO₄ 

Relevant articles and documents

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

Synthesis and fungicidal activity of aryl carbamic acid-5-aryl-2- furanmethyl ester

Chitin, a major structural component of insect cuticle and fungus cell wall but absent in plants and vertebrates, is regarded as a safe and selective target for pest control agents. Chitin synthesis inhibitors (CSIs) have been well-known as insect growth regulators (IGRs) but rarely found as fungicides in agriculture. To find novel CSIs with good activity, benzoylphenylurea, a typical kind of CSIs, was chosen as the lead compound and 26 novel aryl carbamic acid-5-aryl-2-furanmethyl esters were designed by converting the urea linkages of benzoylphenylureas to carbamic acid esters and changing the aniline parts into furanmethyl groups. The title compounds were synthesized and their structures confirmed by IR, 1H NMR, and elemental analysis. Preliminary insecticidal and fungicidal bioassays were carried out. The results indicated that the title compounds had no insecticidal effect on Culex pipiens pallens and Plutella xylostella Linnaeus, but most compounds exhibited good fungicidal activities against Corynespora cassiicola, Thanatephorus cucumeris, Botrytis cinerea, and Fusarium oxysporum. In particular, compounds V-4, V-6, V-7, and V-8 showed better activities against the four strains than those of the commercialized fungicides. The morphologic result suggested that compound V-21 had disturbed the cell wall formation of C. cassiicola. The results indicated that modification on the urea linkage of benzoylphenylurea was an effective way to discover new candidates for fungicides.