40322-20-1

Basic information

• Product Name: 1H-1,2,4-Triazole-1-carboxylic acid, methyl ester (9CI)
• Synonyms: 1H-1,2,4-Triazole-1-carboxylic acid, methyl ester (9CI)
• CAS NO: 40322-20-1
• Molecular Formula: C4H5N3O2
• Molecular Weight: 127.1014
• Product Categories: ACIDHALIDE
• Mol File: 40322-20-1.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-1,2,4-Triazole-1-carboxylic acid, methyl ester (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1,2,4-Triazole-1-carboxylic acid, methyl ester (9CI)(40322-20-1)
• EPA Substance Registry System: 1H-1,2,4-Triazole-1-carboxylic acid, methyl ester (9CI)(40322-20-1)

Safety Data

• Hazardous Substances Data: 40322-20-1(Hazardous Substances Data)

Upstream product

• 288-88-0 1,2,4-Triazole 
• 79-22-1 methyl chloroformate 

Relevant articles and documents

Alkylation, Acylation and Silylation of Azoles

Performing alkylation, acylation and silylation reactions in separate deprotonation and nucleophilic displacement steps allows for better control of reaction conditions and facilitates problem handling in these processes.In the alkylation of azoles the alkylating agents and solvents possess individual reaction capabilities which seem to be approximately additive.Monoalkylation occurs if the sum of the normalized reaction potentials is equal or larger than the pKa value of the azole.Dialkylation is avoided by keeping the sum of the normalized reaction potentials below the pKa value of the alkylazole.The applicability of these principles is demonstrated by the development of effective procedures for the methylation, benzylation, acetylation, methoxycarbonylation and trimethylsilylation of azoles.