40345-75-3Relevant academic research and scientific papers
The synthesis of 2,2-disubstituted 3-nitrochromenes from salicylaldehyde and 2,2-disubstituted 1-nitroalkenes
Yan, Ming-Chung,Jang, Yeong-Jiunn,Kuo, Wen-Yu,Tu, Zhijay,Shen, Kao-Hsien,Cuo, Ting-Shen,Ueng, Chuen-Her,Yao, Ching-Fa
, p. 1033 - 1048 (2007/10/03)
Reactions of salicylaldehyde (1) with β-nitrostyrenes (2), (4), and (6) in the presence of 1,4-diazabicyclo[2.2.2] octane (DABCO) without the use of solvent at 40 °C gave high yields of the corresponding 3-nitrochromenes, respectively. Other conjugated ni
An easy and efficient method for the synthesis of 2,2-dialkyl-3-nitrochromene
Yan, Ming-Chung,Jang, Yeong-Jiunn,Yao, Ching-Fa
, p. 2717 - 2721 (2015/09/10)
Reactions of salicylaldehyde 1, 1,4-diazabicyclo[2.2.2]octane (DABCO), with β-nitrostyrenes 2, 4, 12, 14, and 16, respectively, in the absence of solvent at 40°C gave high yields of 3-nitro-chromenes. Only 96% of trans-3-nitro-4-hydroxyflavans 7 or 98% of 10 were isolated when compounds 6 or 9 reacted with 1 and DABCO under similar conditions. When the reaction temperature was increased to 90°C, 7 and 10 underwent dehydration to generate 74% of 8 and 89% of 11.
