403477-61-2Relevant articles and documents
A direct and versatile access to α,α-disubstituted 2-pyrrolidinylmethanols by SmI2-mediated reductive coupling
Burchak, Olga N.,Philouze, Christian,Chavant, Pierre Yves,Py, Sandrine
supporting information; experimental part, p. 3021 - 3023 (2009/04/18)
(Chemical Equation Presented) Various α,α-disubstituted 2-pyrrolidinylmethanols are efficiently prepared in a single step from ketones using a SmI2-mediated cross-coupling with 1-pyrroline N-oxide. The N-hydroxy-α,α-diphenylprolinol is also easily prepared and resolved.