403492-07-9Relevant academic research and scientific papers
Pyrazolopyridine compound and pharmaceutical use thereof
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, (2008/06/13)
A pyrazolopyridine compound of formula (I) wherein: R1 is hydrogen, lower alkyl optionally substituted by susbtituent(s), or cyclo(lower)alkyl which may be interrupted by an oxygen or nitrogen atom and optionally substituted by substituent(s); R2 is hydrogen, halogen or lower alkoxy; R3 is a substituent; and n is an integer from 1 to 4, provided R3 may be different from each other when n is 2, 3 or 4, or a salt thereof. The pyrazolopyridine compound (I) and salt thereof of the present invention are adnosine antagonists and are useful for the prevention and/or treatment of depression, dementia (e.g. Alzheimer's disease, cerebrovascular dementia, dementia accompanying Parkinson's disease, etc.) Parkinson's disease, anxiety, pain, cerebrovascular disease (e.g. stroke, etc.), heart failure and the like.
