403502-14-7

Upstream product

• 1160747-09-0 5-(2-nitrophenyl)-1H-pyrrole-2-carboxylic acid ethyl ester 
• 1466-88-2 2-nitrocinnamic aldehyde 
• 403502-29-4 5-(2-nitro-phenyl)-1H-pyrrole-2-carboxylic acid methyl ester 

Downstream Products

• 1072149-61-1 C₁₁H₇ClN₂O₃ 
• 403502-41-0 [5-(2-amino-phenyl)-1H-pyrrol-2-yl]-[4-(3-isopropylamino-pyridin-2-yl)-piperazin-1-yl]-methanone 
• 403502-20-5 [4-(3-isopropylamino-pyridin-2-yl)-piperazin-1-yl]-[5-(2-nitro-phenyl)-1H-pyrrol-2-yl]-methanone 

Relevant academic research and scientific papers

Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors

We have previously described a series of 3-phenyl-4,5-dihydro-1H-pyrazole derivatives as moderately potent nNOS inhibitors. As a follow up of these studies, several new 5-phenyl-1H-pyrrole-2-carboxamide derivatives have been synthesized, and their biologi

NMR and conformational studies of new 5-phenylpyrrole-carboxamide derivatives

The 1H and 13C NMR resonances of 22 5-(5-substituted-2-nitrophenyl)-1H-pyrrole-2-carboxamides, 22 5-(5-substituted-2-aminophenyl)-1H-pyrrole-2-carboxamides, and 9 5-phenyl-1H-pyrrole-2-carboxamides we

Synthesis and anti-HIV-1 activity of new delavirdine analogues carrying arylpyrrole moieties

In our search for novel anti-human immunodeficiency virus (HIV)-1 agents, 14 delavirdine analogues were synthesized and evaluated as potential anti-HIV-1 agents in cell-based assays. Compound 1Aa exhibited potent and selective anti-HIV-1 activity in acutely infected MT4 cells, with effective concentration (EC50) values in the submicromolar range.