Basic information

Product Name: Z-PYR-ONP
Synonyms: Z-PYR-ONP;Z-PYROGLUTAMIC ACID-ONP;Z-L-PYROGLUTAMIC ACID 4-NITROPHENYL ESTER;(S)-N-alpha-Benzyloxycarbonyl-pyroglutamic acid p-nitrophenyl ester;Z-L-Pyr-ONp;(2S)-5-Oxo-1,2-pyrrolidinedicarboxylic acid 2-(4-nitrophenyl)1-benzyl ester;(S)-1-Benzyl 2-(4-nitrophenyl) 5-oxopyrrolidine-1,2-dicarboxylate;Z-L-pyroglutamic acid 4-nitrophenyl ester99%
CAS NO:40356-52-3
Molecular Formula: C19H16N2O7
Molecular Weight: 384.34
EINECS: N/A
Product Categories: Amino Acid Derivatives
Mol File: 40356-52-3.mol

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: /
Density: N/A
Refractive Index: N/A
Storage Temp.: -15°C
Solubility: N/A
CAS DataBase Reference: Z-PYR-ONP(CAS DataBase Reference)
NIST Chemistry Reference: Z-PYR-ONP(40356-52-3)
EPA Substance Registry System: Z-PYR-ONP(40356-52-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 40356-52-3(Hazardous Substances Data)

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40356-52-3 Usage

Uses

Used in Biochemistry and Pharmaceutical Research:
Z-PYR-ONP is used as a fluorescent substrate for the measurement of peptidase and glycosidase activities, enabling the study of enzyme kinetics and inhibition. Its fluorescent properties allow for the detection and quantification of enzymatic activity, making it a valuable tool in understanding enzyme mechanisms and their role in various biological processes.
Used in High-Throughput Screening Assays:
Z-PYR-ONP is used as a screening tool in high-throughput assays to identify potential drug candidates and inhibitors. Its ability to measure enzymatic activity in a rapid and sensitive manner makes it an ideal choice for large-scale screening efforts, facilitating the discovery of new therapeutic agents and their optimization for specific applications.
Used in Enzyme Kinetics Studies:
Z-PYR-ONP is used as a substrate in enzyme kinetics studies to determine the rate of enzymatic reactions and the affinity of enzymes for their substrates. By monitoring the fluorescence emitted upon substrate cleavage, researchers can gain insights into the catalytic efficiency and specificity of enzymes, contributing to the development of targeted therapies and diagnostic tools.
Used in Drug Development:
Z-PYR-ONP is used in the development of drugs targeting specific enzymes, as its fluorescent properties allow for the assessment of enzyme inhibition and the identification of potential lead compounds. By monitoring the interaction between Z-PYR-ONP and candidate molecules, researchers can evaluate the potency and selectivity of potential drugs, guiding the optimization of drug candidates for therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 40356-52-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,5 and 6 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 40356-52:
(7*4)+(6*0)+(5*3)+(4*5)+(3*6)+(2*5)+(1*2)=93
93 % 10 = 3
So 40356-52-3 is a valid CAS Registry Number.

40356-52-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-O-benzyl 2-O-(4-nitrophenyl) (2S)-5-oxopyrrolidine-1,2-dicarboxylate

1.2 Other means of identification

Product number	-
Other names	Z-Pyr-ONp

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40356-52-3 SDS

40356-52-3Upstream product

40356-52-3Downstream Products

42533-70-0 Z-Pyr-His-Pro-NH₂

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